Publication: Antiplasmodial, antimycobacterial, and cytotoxic principles from Camchaya calcarea
| dc.contributor.author | Namphung Vongvanich | en_US |
| dc.contributor.author | Prasat Kittakoop | en_US |
| dc.contributor.author | Panarat Charoenchai | en_US |
| dc.contributor.author | Sutichai Intamas | en_US |
| dc.contributor.author | Kanlayanee Sriklung | en_US |
| dc.contributor.author | Yodhathai Thebtaranonth | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Thailand National Center for Genetic Engineering and Biotechnology | en_US |
| dc.contributor.other | Chulabhorn Research Institute | en_US |
| dc.date.accessioned | 2018-08-20T06:47:27Z | |
| dc.date.available | 2018-08-20T06:47:27Z | |
| dc.date.issued | 2006-12-01 | en_US |
| dc.description.abstract | Chemical exploration of Camchaya calcarea (family Compositae) has led to the isolation of nine known sesquiterpene lactones 1-9, together with caffeic acid methyl ester 10. Sesquiterpenes 1, 2, 3, 4, 5, 7, and 8 exhibited moderate antiplasmodial activity, but showed potent antimycobacterial activity. Interestingly, the cytotoxicity of sesquiterpene lactones 1, 2, and 4 towards small-cell lung cancer cell line (NCI-H187) is stronger (two orders of magnitude) than towards the Vero cell line. Caffeic acid methyl ester (10) was cytotoxic against NCI-H187 and BC cell lines, however the ester 10 showed only mild antimycobacterial activity. © Georg Thieme Verlag KG Stuttgart. | en_US |
| dc.identifier.citation | Planta Medica. Vol.72, No.15 (2006), 1427-1430 | en_US |
| dc.identifier.doi | 10.1055/s-2006-951711 | en_US |
| dc.identifier.issn | 00320943 | en_US |
| dc.identifier.other | 2-s2.0-33846213131 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/22853 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846213131&origin=inward | en_US |
| dc.subject | Agricultural and Biological Sciences | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Antiplasmodial, antimycobacterial, and cytotoxic principles from Camchaya calcarea | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846213131&origin=inward | en_US |