Publication:
Pyrrolidine and α-methylene-α-lactam from the cyclization of α-(alkylaminoethyl)acrylate: Synthesis of aza-sarkomycins

dc.contributor.authorBonkoch Tarnchompooen_US
dc.contributor.authorChachanat Thebtaranonthen_US
dc.contributor.authorYodhathai Thebtaranonthen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-06-14T09:01:05Z
dc.date.available2018-06-14T09:01:05Z
dc.date.issued1987-01-01en_US
dc.description.abstractDiene 1 readily adds primary amines to give 2 which can cyclize either in a Michael addition fashion or via a displacement reaction to give, respectively, pyrrolidine 3 or methylene lactam 4 which further isomerizes to 5 under the employed reaction conditions. Compound 4 can be obtained as the sole product from the reaction of diene precursor 7 with amines followed by vacuum pyrolysis. © 1987.en_US
dc.identifier.citationTetrahedron Letters. Vol.28, No.52 (1987), 6675-6678en_US
dc.identifier.doi10.1016/S0040-4039(00)96943-0en_US
dc.identifier.issn00404039en_US
dc.identifier.other2-s2.0-0023579210en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/15321
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0023579210&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titlePyrrolidine and α-methylene-α-lactam from the cyclization of α-(alkylaminoethyl)acrylate: Synthesis of aza-sarkomycinsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0023579210&origin=inwarden_US

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