Publication: No evidence of cardiotoxicity during antimalarial treatment with artemether-lumefantrine
| dc.contributor.author | M. Van Vugt | en_US |
| dc.contributor.author | F. Ezzet | en_US |
| dc.contributor.author | F. Nosten | en_US |
| dc.contributor.author | I. Gathmann | en_US |
| dc.contributor.author | P. Wilairatana | en_US |
| dc.contributor.author | S. Looareesuwan | en_US |
| dc.contributor.author | N. J. White | en_US |
| dc.contributor.other | Shoklo Malaria Research Unit | en_US |
| dc.contributor.other | Academic Medical Centre, University of Amsterdam | en_US |
| dc.contributor.other | Novartis International AG | en_US |
| dc.contributor.other | John Radcliffe Hospital | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-09-07T08:52:08Z | |
| dc.date.available | 2018-09-07T08:52:08Z | |
| dc.date.issued | 1999-01-01 | en_US |
| dc.description.abstract | Artemether-lumefantrine is a new fixed antimalarial combination effective against multidrug-resistant falciparum malaria. A prospective electrocardiographic study was conducted in 150 patients receiving artemether-lumefantrine and 50 treated with artesunate-mefloquine. There was no evidence for clinically significant changes in the electrocardiographic intervals and in particular no relationship between plasma concentrations of lumefantrine and QTc prolongation. Artemether-lumefantrine does not have significant cardiac effects at therapeutic doses. | en_US |
| dc.identifier.citation | American Journal of Tropical Medicine and Hygiene. Vol.61, No.6 (1999), 964-967 | en_US |
| dc.identifier.doi | 10.4269/ajtmh.1999.61.964 | en_US |
| dc.identifier.issn | 00029637 | en_US |
| dc.identifier.other | 2-s2.0-0033386669 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/25476 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0033386669&origin=inward | en_US |
| dc.subject | Immunology and Microbiology | en_US |
| dc.subject | Medicine | en_US |
| dc.title | No evidence of cardiotoxicity during antimalarial treatment with artemether-lumefantrine | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0033386669&origin=inward | en_US |