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New Fluorene Derivatives from Dendrobium gibsonii and Their α-Glucosidase Inhibitory Activity

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dc.contributor.authorMay Thazin Thanten_US
dc.contributor.authorNutputsorn Chatsumpunen_US
dc.contributor.authorWanwimon Mekboonsonglarpen_US
dc.contributor.authorBoonchoo Sritularaken_US
dc.contributor.authorKittisak Likhitwitayawuiden_US
dc.contributor.otherChulalongkorn Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2020-11-18T08:01:00Z
dc.date.available2020-11-18T08:01:00Z
dc.date.issued2020-10-25en_US
dc.description.abstractTwo new compounds, dihydrodengibsinin (1) and dendrogibsol (2), were isolated from the whole plant of Dendrobium gibsonii, together with seven known compounds (3-9). The structures of the new compounds were elucidated by their spectroscopic data. All these isolates were evaluated for their α-glucosidase inhibitory activities. Dendrogibsol (2) and lusianthridin (7) showed strong α-glucosidase inhibitory activity when compared with acarbose. An enzyme kinetic study revealed that dendrogibsol (2) is a noncompetitive inhibitor of α-glucosidase.en_US
dc.identifier.citationMolecules (Basel, Switzerland). Vol.25, No.21 (2020)en_US
dc.identifier.doi10.3390/molecules25214931en_US
dc.identifier.issn14203049en_US
dc.identifier.other2-s2.0-85094830587en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/59866
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85094830587&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.titleNew Fluorene Derivatives from Dendrobium gibsonii and Their α-Glucosidase Inhibitory Activityen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85094830587&origin=inwarden_US

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