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A rhodamine-triazole fluorescent chemodosimeter for Cu<sup>2+</sup> detection and its application in bioimaging

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dc.contributor.authorKanokorn Wechakornen_US
dc.contributor.authorSamran Prabpaien_US
dc.contributor.authorKanoknetr Suksenen_US
dc.contributor.authorPhongthon Kanjanasiriraten_US
dc.contributor.authorYongyut Pewkliangen_US
dc.contributor.authorSuparerk Borwornpinyoen_US
dc.contributor.authorPalangpon Kongsaereeen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2019-08-23T10:37:26Z
dc.date.available2019-08-23T10:37:26Z
dc.date.issued2018-02-01en_US
dc.description.abstractCopyright © 2017 John Wiley & Sons, Ltd. A rhodamine-based fluorescent chemodosimeter rhodamine hydrazide-triazole (RHT) tethered with a triazole moiety was developed for Cu2+ detection. In aqueous medium, the RHT probe exhibited high selectivity and sensitivity toward Cu2+ among other metal ions. The addition of Cu2+ triggered a fluorescence emission of RHT by 384-fold (Φ = 0.33) based on a ring-opening process and a subsequent hydrolysis reaction. Moreover, RHT also showed a selective colorimetric response toward Cu2+ from colorless solution to pink, readily observed with the naked eye. The limit of detection of RHT for Cu2+ was calculated to be 1 nM (0.06 ppb). RHT was successfully demonstrated to detect Cu2+ in Chang liver cells by confocal fluorescence microscopy.en_US
dc.identifier.citationLuminescence. Vol.33, No.1 (2018), 64-70en_US
dc.identifier.doi10.1002/bio.3373en_US
dc.identifier.issn15227243en_US
dc.identifier.issn15227235en_US
dc.identifier.other2-s2.0-85024100001en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/45250
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85024100001&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.titleA rhodamine-triazole fluorescent chemodosimeter for Cu<sup>2+</sup> detection and its application in bioimagingen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85024100001&origin=inwarden_US

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