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Inhibition of intestinal glucose absorption in several animal species by cytochalasins

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dc.contributor.authorC. Toskulkaoen_US
dc.contributor.authorT. Glinsukonen_US
dc.contributor.authorB. Kongsuktrakoonen_US
dc.contributor.authorS. Sophasanen_US
dc.contributor.authorW. Thamaviten_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-04-30T08:38:17Z
dc.date.available2018-04-30T08:38:17Z
dc.date.issued1980-12-01en_US
dc.description.abstractThe effect of various cytochalasins on intestinal glucose absorption in several animal species was investigated in vitro. Glucose absorption in mouse jejunum was highly inhibited (68.1%) by cytochalasin E (25.0 μg/ml) within 30-min incubation and less extent in rat (48.9%), hamster (34.1%), frog (28.1%), guinea pig (27.5%), rabbit (24.3%) and turtle jejunum (22.7%). Among cytochalasins A, B, C, D and E, cytochalasin E was a most potent derivative that could inhibit glucose absorption by up to 55.5% at a concentration of only 5.0 μg/ml in mouse jejunum and its effect may possibly be related to the formation of mini villi and the intracellular vacuoles in the intestinal absorptive cells.en_US
dc.identifier.citationResearch Communications in Chemical Pathology and Pharmacology. Vol.30, No.3 (1980), 521-534en_US
dc.identifier.issn00345164en_US
dc.identifier.other2-s2.0-0019179003en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/11186
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0019179003&origin=inwarden_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleInhibition of intestinal glucose absorption in several animal species by cytochalasinsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0019179003&origin=inwarden_US

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