Publication: 11-Hydroxymonocerin from the plant endophytic fungus Exserohilum rostratum
| dc.contributor.author | Ruengrit Sappapan | en_US |
| dc.contributor.author | Damrong Sommit | en_US |
| dc.contributor.author | Nattaya Ngamrojanavanich | en_US |
| dc.contributor.author | Somchai Pengpreecha | en_US |
| dc.contributor.author | Suthep Wiyakrutta | en_US |
| dc.contributor.author | Nongluksna Sriubolmas | en_US |
| dc.contributor.author | Khanitha Pudhom | en_US |
| dc.contributor.other | Chulalongkorn University | en_US |
| dc.contributor.other | Mahanakorn University of Technology | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-07-12T02:17:34Z | |
| dc.date.available | 2018-07-12T02:17:34Z | |
| dc.date.issued | 2008-09-01 | en_US |
| dc.description.abstract | A new analogue of monocerin, 11-hydroxymonocerin (2), along with monocerin (1) and 12-hydroxymonocerin (3) were isolated from cultures of Exserohilum rostratum, a fungal strain endophytic in Stemona sp. The structure of 2 was determined by analysis of NMR and MS data and by comparison of spectroscopic data to those of 1. Monocerin (1) and 11-hydroxymonocerin (2) displayed activity against Plasmodium falciparum (K1, multidrug-resistant strain) with IC 50 values of 0.68 and 7.70 μM, respectively. None of the compounds were cytotoxic against any of the tumor cell lines tested. © 2008 American Chemical Society and American Society of Pharmacognosy. | en_US |
| dc.identifier.citation | Journal of Natural Products. Vol.71, No.9 (2008), 1657-1659 | en_US |
| dc.identifier.doi | 10.1021/np8004024 | en_US |
| dc.identifier.issn | 01633864 | en_US |
| dc.identifier.other | 2-s2.0-54149106109 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/18870 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=54149106109&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Medicine | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | 11-Hydroxymonocerin from the plant endophytic fungus Exserohilum rostratum | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=54149106109&origin=inward | en_US |