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Crossed immunoelectrophoresis for the detection of split products of the third complement component in dengue hemorrhagic fever. II. In vitro activation by dengue viral antigen

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dc.contributor.authorV. Churdbooncharten_US
dc.contributor.authorN. Bhamarapravatien_US
dc.contributor.authorS. Yoksanen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-10-12T07:41:42Z
dc.date.available2018-10-12T07:41:42Z
dc.date.issued1984-01-01en_US
dc.description.abstractThe ability of dengue viral antigen(s) from different sources, and preformed antigen-antibody complexes, to activate the third component of human complement (C3) in vitro was demonstrated by using split products of human C3. Dengue type 2 viral antigen(s) from suckling mouse brain and from infected monocytes activated C3 via the alternative pathway, while preformed soluble dengue-2 antibody complex activated mainly the classical pathway. The implications of this finding for the pathogenesis of dengue hemorrhagic fever are discussed.en_US
dc.identifier.citationAmerican Journal of Tropical Medicine and Hygiene. Vol.33, No.6 (1984), 1239-1247en_US
dc.identifier.doi10.4269/ajtmh.1984.33.1239en_US
dc.identifier.issn00029637en_US
dc.identifier.other2-s2.0-0021716314en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/30613
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021716314&origin=inwarden_US
dc.subjectImmunology and Microbiologyen_US
dc.subjectMedicineen_US
dc.titleCrossed immunoelectrophoresis for the detection of split products of the third complement component in dengue hemorrhagic fever. II. In vitro activation by dengue viral antigenen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021716314&origin=inwarden_US

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