Publication: Maternal and viral factors in vertical transmission of HIV-1 subtype E
| dc.contributor.author | Ruengpung Sutthent | en_US |
| dc.contributor.author | Suporn Foongladda | en_US |
| dc.contributor.author | Sanay Chearskul | en_US |
| dc.contributor.author | Niran Wanaprapa | en_US |
| dc.contributor.author | Sirirat Likanonskul | en_US |
| dc.contributor.author | Uraiwan Kositanont | en_US |
| dc.contributor.author | Suda Riengrojpitak | en_US |
| dc.contributor.author | Somphong Sahapong | en_US |
| dc.contributor.author | Chantapong Wasi | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Bamrasnadura Hospital | en_US |
| dc.contributor.other | Faculty of Medicine, Siriraj Hospital, Mahidol University | en_US |
| dc.date.accessioned | 2018-07-04T07:46:45Z | |
| dc.date.available | 2018-07-04T07:46:45Z | |
| dc.date.issued | 1997-12-01 | en_US |
| dc.description.abstract | Vertical transmission of HIV-1 is caused by multifactorial factors. To access the relationship of viral factors involving in perinatal transmission of HIV-1 subtype E, which is the predominant type in Thailand, plasma viral load, blood CD4+ lymphocyte level, heteroduplex mobility, and V3 sequence of the HIV-1 envelope gene were studied in 32 transmitting and 25 non-transmitting mothers. We found that HIV-1 subtype E vertical transmission was strongly associated with high maternal plasma viral RNA (> 4 × 104 copies/ml) and high genetic diversity of envelope gene determined by heteroduplex mobility (< 0.9). The variation of nucleotide sequences in envelope gene of subtype E vertical transmission could not determine in V3 region. Hence, plasma viral load and heteroduplex mobility can be used as prediction factors in vertical transmission of HIV-1 subtype E. | en_US |
| dc.identifier.citation | Southeast Asian Journal of Tropical Medicine and Public Health. Vol.28, No.4 (1997), 689-698 | en_US |
| dc.identifier.issn | 01251562 | en_US |
| dc.identifier.other | 2-s2.0-0031301530 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/18046 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0031301530&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Maternal and viral factors in vertical transmission of HIV-1 subtype E | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0031301530&origin=inward | en_US |