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Linking dengue virus entry and translation/replication through amphisomes

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dc.contributor.authorMingkwan Panyasrivaniten_US
dc.contributor.authorAtefeh Khakpooren_US
dc.contributor.authorNitwara Wikanen_US
dc.contributor.authorDuncan R. Smithen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-09-13T06:25:35Z
dc.date.available2018-09-13T06:25:35Z
dc.date.issued2009-04-01en_US
dc.description.abstractAmphisomes are preautolysosomal vacuoles formed upon the fusion of autophagosomes with endosomes, and as such represent a critical meeting point between endocytic and autophagic pathways. Dengue virus enters into susceptible cells by clathrin-mediated endocytosis, and colocalization of dengue markers with markers of both autophagic and endosomal vesicles demonstrates that amphi-somes are a site of dengue virus replication and translation. This work links for the first time the processes of dengue virus entry and translation/replication, and allows for interpretation of the early part of the dengue virus life cycle in terms of a continual association with membranes of an endosomal-autophagosomal lineage. © 2009 Landes Bioscience.en_US
dc.identifier.citationAutophagy. Vol.5, No.3 (2009), 434-435en_US
dc.identifier.doi10.4161/auto.5.3.7925en_US
dc.identifier.issn15548635en_US
dc.identifier.issn15548627en_US
dc.identifier.other2-s2.0-65249100786en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/27249
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=65249100786&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleLinking dengue virus entry and translation/replication through amphisomesen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=65249100786&origin=inwarden_US

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