Publication: The prediction of GAG and ENV gene on epidemiology of HIV-1 infection in Thailand
| dc.contributor.author | B. Sermsaksakul | en_US |
| dc.contributor.author | S. Sonprasert | en_US |
| dc.contributor.author | N. Horthongkham | en_US |
| dc.contributor.author | P. Ammaranond | en_US |
| dc.contributor.other | Chulalongkorn University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-11-09T03:11:05Z | |
| dc.date.available | 2018-11-09T03:11:05Z | |
| dc.date.issued | 2014-01-01 | en_US |
| dc.description.abstract | © 2014, Journal of Chemical and Pharmaceutical Research. All rights reserved. HIV was classified into 3 groups: group M, N and O. Group M is an important group for epidemiolody. In Thailand, CRF01_AE and B are the most common subtype. Because of heterogeneity HIV can recombine genes to another subtype and cause a new subtype. Forty-two plasma samples from HIV-infected patients were collected at Siriraj Hospital. Specific region of p17 (gag) and C2-V4 (env) genes of HIV were amplified by nested RT-PCR. PCR products were sequenced. Phylogenetic tree was constructed for epidemiological study. Results showed that phylogenetic analysis on env gene was found 100% of HIV subtype CRF01_AE (42/42). Whereas on gag (p17) gene, 69% and 31% were found in CRF01_AE and CRF15_01B subtype, respectively. | en_US |
| dc.identifier.citation | Journal of Chemical and Pharmaceutical Research. Vol.6, No.7 (2014), 2327-2332 | en_US |
| dc.identifier.issn | 09757384 | en_US |
| dc.identifier.other | 2-s2.0-84907235537 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/34910 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84907235537&origin=inward | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | The prediction of GAG and ENV gene on epidemiology of HIV-1 infection in Thailand | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84907235537&origin=inward | en_US |