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Boesenmaxane Diterpenoids from Boesenbergia maxwellii

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dc.contributor.authorThe S. Moeen_US
dc.contributor.authorSuppisak Chaturonrutsameeen_US
dc.contributor.authorSamreang Bunteangen_US
dc.contributor.authorChutima Kuhakarnen_US
dc.contributor.authorSamran Prabpaien_US
dc.contributor.authorPanida Surawatanawongen_US
dc.contributor.authorArthit Chairoungduaen_US
dc.contributor.authorKanoknetr Suksenen_US
dc.contributor.authorRadeekorn Akkarawongsapaten_US
dc.contributor.authorJitra Limthongkulen_US
dc.contributor.authorChanita Napaswaden_US
dc.contributor.authorNarong Nuntasaenen_US
dc.contributor.authorVichai Reutrakulen_US
dc.contributor.otherThailand Ministry of Natural Resources and Environmenten_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherLtd.en_US
dc.contributor.otherMinistry of Educationen_US
dc.date.accessioned2022-08-04T08:11:53Z
dc.date.available2022-08-04T08:11:53Z
dc.date.issued2021-02-26en_US
dc.description.abstractThree new diterpenoids, boesenmaxanes A-C (1-3), with an unprecedented core skeleton consisting of an unusual C-C bond between C-12 and an exo-cyclic methylene C-13, were isolated from the rhizome extracts of Boesenbergia maxwellii. The structures were elucidated by analysis of spectroscopic and X-ray diffraction data. Electronic circular dichroism spectra were used to determine the absolute configuration. All the isolates were evaluated for their cytotoxic effects, anti-HIV activity, and antimicrobial activity. Boesenmaxanes A and C (1 and 3) showed significant inhibitory activity in the syncytium reduction assay, with EC50 values of 55.2 and 27.5 μM, respectively.en_US
dc.identifier.citationJournal of Natural Products. Vol.84, No.2 (2021), 518-526en_US
dc.identifier.doi10.1021/acs.jnatprod.0c00629en_US
dc.identifier.issn15206025en_US
dc.identifier.issn01633864en_US
dc.identifier.other2-s2.0-85099089779en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/76275
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85099089779&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectMedicineen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleBoesenmaxane Diterpenoids from Boesenbergia maxwelliien_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85099089779&origin=inwarden_US

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