Publication: Unstable vancomycin heteroresistance is common among clinical isolates of methiciliin-resistant Staphylococcus aureus
| dc.contributor.author | Nottasorn Plipat | en_US |
| dc.contributor.author | Gilat Livni | en_US |
| dc.contributor.author | Heidi Bertram | en_US |
| dc.contributor.author | Richard B. Thomson | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Schneider Childrens Medical Center Israel | en_US |
| dc.contributor.other | Department of Pathology and Laboratory Medicine | en_US |
| dc.contributor.other | Northwestern University Feinberg School of Medicine | en_US |
| dc.date.accessioned | 2018-06-21T08:28:10Z | |
| dc.date.available | 2018-06-21T08:28:10Z | |
| dc.date.issued | 2005-05-01 | en_US |
| dc.description.abstract | We tested 109 unique, vancomycin-susceptible, methicillin-resistant Staphylococcus aureus (MRSA) strains for vancomycin heteroresistance by a selection method, i.e., step-wise exposure of large inoculums to increasing concentrations of vancomycin. Although no strains demonstrated stable heteroresistance, 81 strains (74%) demonstrated unstable heteroresistance. Unstable heteroresistance is common among clinical isolates of MRSA and may represent a cause of therapeutic failure. Copyright © 2005, American Society for Microbiology. All Rights Reserved. | en_US |
| dc.identifier.citation | Journal of Clinical Microbiology. Vol.43, No.5 (2005), 2494-2496 | en_US |
| dc.identifier.doi | 10.1128/JCM.43.5.2494-2496.2005 | en_US |
| dc.identifier.issn | 00951137 | en_US |
| dc.identifier.other | 2-s2.0-18544374025 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/16994 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=18544374025&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Unstable vancomycin heteroresistance is common among clinical isolates of methiciliin-resistant Staphylococcus aureus | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=18544374025&origin=inward | en_US |