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Synthesis of ethyl 5-phenyl-6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate Derivatives and evaluation of their antimalarial activities

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dc.contributor.authorNongpanga Ningsanonten_US
dc.contributor.authorDavid St C Blacken_US
dc.contributor.authorRachada Chanphenen_US
dc.contributor.authorYodhathai Thebtaranonthen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherUniversity of New South Wales (UNSW) Australiaen_US
dc.contributor.otherThailand National Center for Genetic Engineering and Biotechnologyen_US
dc.date.accessioned2018-07-24T03:19:42Z
dc.date.available2018-07-24T03:19:42Z
dc.date.issued2003-06-05en_US
dc.description.abstractDerivatives of ethyl 5-phenyl-6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate (14-20), with side chains varying from three to five carbon atoms and bearing various substituents, have been prepared from ethyl 2-phenyl-1-pyrroline-5-carboxylate (12). Their in vitro activity against P. falciparum (K1 strain) and antimycobacterium and also their cytotoxic activity against Vero cell have been evaluated.en_US
dc.identifier.citationJournal of Medicinal Chemistry. Vol.46, No.12 (2003), 2397-2403en_US
dc.identifier.doi10.1021/jm020452hen_US
dc.identifier.issn00222623en_US
dc.identifier.other2-s2.0-0038101387en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/20720
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0038101387&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleSynthesis of ethyl 5-phenyl-6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate Derivatives and evaluation of their antimalarial activitiesen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0038101387&origin=inwarden_US

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