Publication: Bacterial Diversity and Phylogenetic Analysis of Type II Polyketide Synthase Gene from Manao-Pee Cave, Thailand
| dc.contributor.author | Apirak Wiseschart | en_US |
| dc.contributor.author | Wuttichai Mhuanthong | en_US |
| dc.contributor.author | Pattamaporn Thongkam | en_US |
| dc.contributor.author | Sithichoke Tangphatsornruang | en_US |
| dc.contributor.author | Duriya Chantasingh | en_US |
| dc.contributor.author | Kusol Pootanakit | en_US |
| dc.contributor.other | Silpakorn University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Thailand National Center for Genetic Engineering and Biotechnology | en_US |
| dc.date.accessioned | 2019-08-23T11:02:04Z | |
| dc.date.available | 2019-08-23T11:02:04Z | |
| dc.date.issued | 2018-07-03 | en_US |
| dc.description.abstract | © 2018 Informa UK Limited, trading as Taylor & Francis Group. A subterranean limestone cave, Manao-Pee, was investigated for bacterial diversity and potential secondary metabolites production. Comparative 16 S rRNA analysis revealed that cave soil was highly dominated by Actinobacteria; whereas, Proteobacteria was highly abundant outside the cave. As Actinobacteria are biotechnologically valuable for their secondary metabolites, the diversity of the β-ketoacyl synthase (KSβ) was investigated. The results showed that the identified KSβhas 61–80% amino acid sequence identity to known sequences. Phylogenetic analysis placed some of the sequences in novel clades, suggesting the presence of novel KSβdomains. Thus, Manao-Pee cave is a promising habitat to discover potential novel bioactive compounds. | en_US |
| dc.identifier.citation | Geomicrobiology Journal. Vol.35, No.6 (2018), 518-527 | en_US |
| dc.identifier.doi | 10.1080/01490451.2017.1411993 | en_US |
| dc.identifier.issn | 15210529 | en_US |
| dc.identifier.issn | 01490451 | en_US |
| dc.identifier.other | 2-s2.0-85042078419 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/45737 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85042078419&origin=inward | en_US |
| dc.subject | Earth and Planetary Sciences | en_US |
| dc.subject | Environmental Science | en_US |
| dc.subject | Immunology and Microbiology | en_US |
| dc.title | Bacterial Diversity and Phylogenetic Analysis of Type II Polyketide Synthase Gene from Manao-Pee Cave, Thailand | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85042078419&origin=inward | en_US |