Publication: Patterns of Lumbar Disc Degeneration: Magnetic Resonance Imaging Analysis in Symptomatic Subjects
Issued Date
2021-01-01
Resource Type
ISSN
19767846
19761902
19761902
Other identifier(s)
2-s2.0-85123081703
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Mahidol University
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SCOPUS
Bibliographic Citation
Asian Spine Journal. Vol.15, No.6 (2021), 799-807
Suggested Citation
Monchai Ruangchainikom, Michael D. Daubs, Akinobu Suzuki, Chengjie Xiong, Tetsuo Hayashi, Trevor P. Scott, Kevin Phan, Jeffrey C. Wang Patterns of Lumbar Disc Degeneration: Magnetic Resonance Imaging Analysis in Symptomatic Subjects. Asian Spine Journal. Vol.15, No.6 (2021), 799-807. doi:10.31616/ASJ.2020.0325 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/78525
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Title
Patterns of Lumbar Disc Degeneration: Magnetic Resonance Imaging Analysis in Symptomatic Subjects
Other Contributor(s)
Osaka Metropolitan University
Siriraj Hospital
Spinal Injuries Center
University of Southern California
University of California, Los Angeles
Montefiore Medical Center
UNLV School of Medicine
General Hospital of Central Theater Command of People's Liberation Army
Proliance Orthopaedics and Sports Medicine
Siriraj Hospital
Spinal Injuries Center
University of Southern California
University of California, Los Angeles
Montefiore Medical Center
UNLV School of Medicine
General Hospital of Central Theater Command of People's Liberation Army
Proliance Orthopaedics and Sports Medicine
Abstract
Study Design: Cross-sectional study.Purpose: To evaluate lumbar disc degeneration (LDD) on magnetic resonance imaging (MRI) in symptomatic subjects to accumulate baseline data on the pattern of degeneration.Overview of Literature: LDD plays an important role in the diagnosis and treatment of low-back pain in patients. Few studies have focused on the pattern of LDD to understand how the lumbar spine ages.Methods: This study included 1,095 patients (mean age, 44.29 years; range, 16–85 years) who underwent upright lumbar MRI. LDD was graded into five categories (I–V). Positive LDD was defined as grade III or greater. The prevalence and pattern of LDD were ana-lyzed, and the correlations between age and total grade of LDD were evaluated.Results: The average number of LDD levels and the total grade of LDD increased with age. LDD moved cephalad with age. The rate of LDD increased rapidly during the decade before the prevalence of LDD and became >50%. In the single-level LDD group, the levels L5–S1 were the most common levels (60.3%). In the two-level group, L4–L5 and L5–S1 were the most common levels (53.5%). In the three-level group, L3–L4, L4–L5, and L5–S1 were the most common levels (55.7%). In the multilevel LDD group, contiguous multilevel disc degeneration (CMDD) was more common than the skipped level disc degeneration (SLDD). The levels L4–L5 were the most com-mon levels in the CMDD group, and L5–S1 were the most common levels among SLDD.Conclusions: LDD was found to correlate with age, and the specific patterns and rates of LDD depended on lumbar disc level and age. These LDD pattern data can be used before spinal procedures to predict the probability of natural LDD progression with age.