Publication: Lakoochins A and B, New Antimycobacterial Stilbene Derivatives from Artocarpus lakoocha
| dc.contributor.author | Apirak Puntumchai | en_US |
| dc.contributor.author | Prasat Kittakoop | en_US |
| dc.contributor.author | Shuleewan Rajviroongit | en_US |
| dc.contributor.author | Saovaluk Vimuttipong | en_US |
| dc.contributor.author | Kittisak Likhitwitayawuid | en_US |
| dc.contributor.author | Yodhathai Thebtaranonth | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Thailand National Center for Genetic Engineering and Biotechnology | en_US |
| dc.contributor.other | Chulalongkorn University | en_US |
| dc.date.accessioned | 2018-07-24T03:38:18Z | |
| dc.date.available | 2018-07-24T03:38:18Z | |
| dc.date.issued | 2004-03-01 | en_US |
| dc.description.abstract | Two new stilbene derivatives, lakoochins A (1) and B (2), were isolated from the roots of Artocarpus lakoocha. The structures of 1 and 2 were elucidated by analysis of their spectral data. Lakoochins A (1) and B (2) exhibited antimycobacterial activity with the respective MIC values of 12.5 and 50 μg/mL. While 1 was cytotoxic against the BC (breast cancer) cell line (IC50 6.1 μg/mL) but inactive (at 20 μg/mL) toward KB (nasopharyngeal carcinoma) cells, compound 2 possessed cytotoxicity against the BC and KB cell lines with IC50 values of 3.1 and 6.1 μg/mL, respectively. | en_US |
| dc.identifier.citation | Journal of Natural Products. Vol.67, No.3 (2004), 485-486 | en_US |
| dc.identifier.doi | 10.1021/np030429e | en_US |
| dc.identifier.issn | 01633864 | en_US |
| dc.identifier.other | 2-s2.0-1642506128 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/21222 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=1642506128&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Medicine | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Lakoochins A and B, New Antimycobacterial Stilbene Derivatives from Artocarpus lakoocha | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=1642506128&origin=inward | en_US |