Publication:
Phenylbutazone Plasma Binding: Effects of Salicylic Acid, Indomethacin, and Dicloxacillin

Simple item page
dc.contributor.authorRomeo Quijanoen_US
dc.contributor.authorBunkerd Kongyingyoesen_US
dc.contributor.authorAmnuay Thithapandhaen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-06-01T06:29:30Z
dc.date.available2018-06-01T06:29:30Z
dc.date.issued1979-01-01en_US
dc.description.abstractThe effects of three highly bound acids, viz salicylic acid, indomethacin, and dicloxacillin, on the binding of phenylbutazone to human plasma proteins were studied by equilibrium dialysis. Salicylic acid was found to displace phenylbutazone from its binding sites to a degree which might be clinically significant. Indomethacin caused a slight decrease in the percentage binding of phenylbutazone which is not likely to be of clinical importance. Dicloxacillin, however, did not appear to affect the plasma protein binding of phenylbutazone suggesting that the two drugs could be bound at mutually noninteracting sites in the protein molecule. © 1979, SAGE Publications. All rights reserved.en_US
dc.identifier.citationProceedings of the Society for Experimental Biology and Medicine. Vol.162, No.3 (1979), 442-444en_US
dc.identifier.doi10.3181/00379727-162-40700en_US
dc.identifier.issn15353699en_US
dc.identifier.issn00379727en_US
dc.identifier.other2-s2.0-0018628585en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/13159
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0018628585&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titlePhenylbutazone Plasma Binding: Effects of Salicylic Acid, Indomethacin, and Dicloxacillinen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0018628585&origin=inwarden_US

Files

Collections

Scopus 1969-1990