Publication: Hb Kurosaki [α7(A5)Lys→Glu (4AG→GAG)]: An α2-globin gene mutation found in Thailand
| dc.contributor.author | Lukana Ngiwsara | en_US |
| dc.contributor.author | Chantragan Srisomsap | en_US |
| dc.contributor.author | Pranee Winichagoon | en_US |
| dc.contributor.author | Suthat Fucharoen | en_US |
| dc.contributor.author | Bussara Sae-Ngow | en_US |
| dc.contributor.author | Jisnuson Svasti | en_US |
| dc.contributor.other | Chulabhorn Research Institute | en_US |
| dc.contributor.other | The Institute of Science and Technology for Research and Development, Mahidol University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-06-21T08:09:25Z | |
| dc.date.available | 2018-06-21T08:09:25Z | |
| dc.date.issued | 2005-05-30 | en_US |
| dc.description.abstract | Hb Kurosaki [α7(A5)Lys→Glu (AAG→GAG)], has been found for the first time in Thailand. The 30-year-old Thai male had a normal hematological profile at the steady state, but showed an abnormal hemoglobin (Hb) present at a level of 28%. Protein characterization was performed by automated sequencer analysis of the abnormal α-globin chain and amino acid analysis of the abnormal αT-1,2 peptide. Direct DNA sequence analysis of selectively amplified segments of the α1 and α2 genes showed that codon 7 of the α2-globin gene was heterozygous for AAG (Lys) and GAG (Glu). This was confirmed by restriction endonuclease digestion with Eco31I. Copyright © 2005 Taylor & Francis, Inc. | en_US |
| dc.identifier.citation | Hemoglobin. Vol.29, No.2 (2005), 155-159 | en_US |
| dc.identifier.doi | 10.1081/HEM-200058595 | en_US |
| dc.identifier.issn | 03630269 | en_US |
| dc.identifier.other | 2-s2.0-18844422757 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/16342 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=18844422757&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Hb Kurosaki [α7(A5)Lys→Glu (4AG→GAG)]: An α2-globin gene mutation found in Thailand | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=18844422757&origin=inward | en_US |