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Studies on aristolochia III. isolation and biological evaluation of constituents of aristolochia indica roots for fertility-regulating activity<sup>1</sup>

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dc.contributor.authorMohamed S. Ahmeden_US
dc.contributor.authorSam S. Kangen_US
dc.contributor.authorPathmanayaki Rajamahendranen_US
dc.contributor.authorNuntavan Bunyapraphatsaraen_US
dc.contributor.authorR. O.B. Wijesekeraen_US
dc.contributor.authorChun Tao Cheen_US
dc.contributor.authorDonald P. Walleren_US
dc.contributor.authorA. S. Bingelen_US
dc.contributor.authorAnnamarie Martinen_US
dc.contributor.authorDavid C. Lankinen_US
dc.contributor.authorGeoffrey A. Cordellen_US
dc.contributor.authorDjaja D. Soejartoen_US
dc.contributor.authorHarry H.S. Fongen_US
dc.contributor.otherCairo University Faculty of Pharmacyen_US
dc.contributor.otherSeoul National Universityen_US
dc.contributor.otherUniversity of Colomboen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherUnited Nations Industrial Development Organizationen_US
dc.contributor.otherUniversity of Illinois Medical Centeren_US
dc.date.accessioned2018-10-12T07:40:37Z
dc.date.available2018-10-12T07:40:37Z
dc.date.issued1984-01-01en_US
dc.description.abstractethanol extract of Aristolochia indica roots decreased fertility in both rats and hamsters when administered postcoitally (days 1-10 and 1-6, respectively). Petroleum ether (A), CHCl3(B), and aqueous (C) fractions, tested similarly in rats, were inactive and/or toxic. Partition of fraction B afforded non-acidic (D) and acidic (E) fractions. Savinin (1), isolated from fraction D and not previously reported from the Aristolochiaceae, was inactive when administered postcoitally to rats. Aristolochic acid-I (2), reported previously from A. indica and isolated from fraction E, was inactive when administered postcoitally to rats and toxic when administered postcoitally to hamsters. © 1984, American Chemical Society. All rights reserved.en_US
dc.identifier.citationJournal of Natural Products. Vol.47, No.2 (1984), 331-341en_US
dc.identifier.doi10.1021/np50032a017en_US
dc.identifier.issn15206025en_US
dc.identifier.issn01633864en_US
dc.identifier.other2-s2.0-0021240808en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/30592
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021240808&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectMedicineen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleStudies on aristolochia III. isolation and biological evaluation of constituents of aristolochia indica roots for fertility-regulating activity<sup>1</sup>en_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021240808&origin=inwarden_US

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