Publication: Cytotoxic mycoepoxydiene derivatives from an endophytic fungus Phomopsis sp. isolated from Hydnocarpus anthelminthicus
| dc.contributor.author | Surasak Prachya | en_US |
| dc.contributor.author | Suthep Wiyakrutta | en_US |
| dc.contributor.author | Nongluksna Sriubolmas | en_US |
| dc.contributor.author | Nattaya Ngamrojanavanich | en_US |
| dc.contributor.author | Chulabhorn Mahidol | en_US |
| dc.contributor.author | Somsak Ruchirawat | en_US |
| dc.contributor.author | Prasat Kittakoop | en_US |
| dc.contributor.other | Chulabhorn Research Institute | en_US |
| dc.contributor.other | Chulalongkorn University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | The Institute of Science and Technology for Research and Development, Mahidol University | en_US |
| dc.date.accessioned | 2018-08-24T01:36:59Z | |
| dc.date.available | 2018-08-24T01:36:59Z | |
| dc.date.issued | 2007-10-01 | en_US |
| dc.description.abstract | Mycoepoxydiene (1) and derivatives, deacetylmycoepoxydiene (2) and 2,3-dihydromycoepoxydiene (3), were isolated from a broth extract of the endophytic fungus, Phomopsis sp., which was isolated from a Thai medicinal plant, Hydnocarpus anthelminthicus. Compounds 1 and 2 exhibited potent cytotoxic activity, while a dihydro derivative 3 was inactive. The present work suggests that the α,β-unsaturated lactone moiety in mycoepoxydienes might be responsible for the cytotoxicity. © Georg Thieme Verlag KG Stuttgart. | en_US |
| dc.identifier.citation | Planta Medica. Vol.73, No.13 (2007), 1418-1420 | en_US |
| dc.identifier.doi | 10.1055/s-2007-990240 | en_US |
| dc.identifier.issn | 00320943 | en_US |
| dc.identifier.other | 2-s2.0-36048955511 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/23975 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=36048955511&origin=inward | en_US |
| dc.subject | Agricultural and Biological Sciences | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Cytotoxic mycoepoxydiene derivatives from an endophytic fungus Phomopsis sp. isolated from Hydnocarpus anthelminthicus | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=36048955511&origin=inward | en_US |