Publication: Biological evaluations of fatty acid esters originated during storage of Prasaplai, a Thai traditional medicine
Issued Date
2007-09-01
Resource Type
ISSN
14786427
14786419
14786419
Other identifier(s)
2-s2.0-34547943485
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Natural Product Research. Vol.21, No.11 (2007), 990-997
Suggested Citation
Prasan Tangyuenyongwatana, Wandee Gritsanapan Biological evaluations of fatty acid esters originated during storage of Prasaplai, a Thai traditional medicine. Natural Product Research. Vol.21, No.11 (2007), 990-997. doi:10.1080/14786410701371561 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/23980
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Biological evaluations of fatty acid esters originated during storage of Prasaplai, a Thai traditional medicine
Author(s)
Other Contributor(s)
Abstract
Three fatty acid esters, (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-yl linoleate (1), (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-yl oleate (2), and (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-yl palmitate (3), originated during storage by the interaction of components in Prasaplai, were synthesized. These three artificial esters were subjected to four biological evaluations. All three compounds were active against Mycobacterium tuberculosis H37Ra for which compounds 1 and 3 had inhibitory concentration at 200 μg mL-1while compound 2 inhibited at 100 μg mL-1. When all these compounds were subjected to anti-HSV-1 test, compound 2 showed positive activity at 42.6 μg mL-1without any cytotoxic activity against human vero cell line while compound 3 had the cytotoxicity to vero cell at IC5038 μg mL-1. Compound 1 was inactive for this test.