Publication: Hypoglycemic and hypolipidemic effects of a water extract of Pandanus odorus Ridl. Roots in streptozotocin-diabetic rats
Issued Date
1997-06-01
Resource Type
ISSN
02179687
Other identifier(s)
2-s2.0-0030876366
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Asia Pacific Journal of Pharmacology. Vol.12, No.1-2 (1997), 3-8
Suggested Citation
P. Peungvicha, S. S. Thirawarapan, H. Watanabe Hypoglycemic and hypolipidemic effects of a water extract of Pandanus odorus Ridl. Roots in streptozotocin-diabetic rats. Asia Pacific Journal of Pharmacology. Vol.12, No.1-2 (1997), 3-8. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/18226
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Hypoglycemic and hypolipidemic effects of a water extract of Pandanus odorus Ridl. Roots in streptozotocin-diabetic rats
Author(s)
Other Contributor(s)
Abstract
Plasma glucose and total lipid levels in normal and streptozotocin-diabetic rats were determined after oral administration of a water extract of Pandanus odorus Ridl. root. The oral administration of the water extract at doses of 0.25, 0.5 and 1 g kg-1produced a significant hypoglycemic effect in the intravenous glucose tolerance test and the adrenaline hyperglycemic test. Plasma non-esterified fatty acids were significantly decreased after 1 and 2 hours of single oral administration of the Pandanus extract at doses of 0.25 and 0.5 g kg-1. Plasma cholesterol and triglyceride were also significantly decreased by the extract after once daily oral administration of Pandanus extract at a dose of 0.5 g kg-1for 7 days. These results suggest that a water extract of Pandanus odorus has hypoglycemic and hypolipidemic effects in streptozotocin-diabetic rats.