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Bacillus subtilis SSE4 produces subtulene A, a new lipopeptide antibiotic possessing an unusual C15 unsaturated β-amino acid

dc.contributor.authorNopporn Thasanaen_US
dc.contributor.authorBenjaphorn Prapagdeeen_US
dc.contributor.authorNuchanart Rangkadiloken_US
dc.contributor.authorRatiboot Sallabhanen_US
dc.contributor.authorSeaim Lwin Ayeen_US
dc.contributor.authorSomsak Ruchirawaten_US
dc.contributor.authorSuvit Lopraserten_US
dc.contributor.otherChulabhorn Graduate Instituteen_US
dc.contributor.otherChulabhorn Research Instituteen_US
dc.contributor.otherFaculty of Environment and Resource Studies, Mahidol Universityen_US
dc.contributor.otherCenter of Excellence on Environmental Healthen_US
dc.date.accessioned2018-09-24T08:44:12Z
dc.date.available2018-09-24T08:44:12Z
dc.date.issued2010-07-01en_US
dc.description.abstractSubtulene A, a new cyclic lipopeptide, was isolated from the culture broth of Bacillus subtilis SSE4. This antibiotic compound contained the seven common α-amino acids, l-Asn-1, d-Tyr-2, d-Asn-3, l-Gln-4, l-Pro-5, d-Asn-6, l-Ser-7 and the unique β-amino acid-8 present in the iturin family. 1D and 2D NMR, as well as MS analyses, identified the β-amino acid as 3-amino-13-methyltetradec-8-enoic acid, an Iso C15 long chain β-amino acid. B. subtilis SSE4 was also found to produce iturin A. B. subtilis SSE4 culture filtrate exhibited both antifungal and antibacterial activities. © 2010 Federation of European Biochemical Societies.en_US
dc.identifier.citationFEBS Letters. Vol.584, No.14 (2010), 3209-3214en_US
dc.identifier.doi10.1016/j.febslet.2010.06.005en_US
dc.identifier.issn00145793en_US
dc.identifier.other2-s2.0-77954175684en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/28676
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77954175684&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleBacillus subtilis SSE4 produces subtulene A, a new lipopeptide antibiotic possessing an unusual C15 unsaturated β-amino aciden_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77954175684&origin=inwarden_US

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