Publication: Mukaiyama's reagent promoted C-N bond formation: a new method to synthesize 3-alkylquinazolin-4-ones
| dc.contributor.author | Puminun Punthasee | en_US |
| dc.contributor.author | Avassaya Vanitcha | en_US |
| dc.contributor.author | Sumrit Wacharasindhu | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-09-24T08:46:40Z | |
| dc.date.available | 2018-09-24T08:46:40Z | |
| dc.date.issued | 2010-03-31 | en_US |
| dc.description.abstract | A new approach to synthesize 3-alkylquinazolin-4-ones is developed. Treatment of quinazolin-4-ones with Mukaiyama's reagent, a base and a primary amine nucleophile results in the formation of 3-alkylquinazolin-4-ones in moderate to good yields under mild conditions. Using this methodology, a one-step synthesis of the natural alkaloid, echinozolinone, is accomplished. © 2010 Elsevier Ltd. All rights reserved. | en_US |
| dc.identifier.citation | Tetrahedron Letters. Vol.51, No.13 (2010), 1713-1716 | en_US |
| dc.identifier.doi | 10.1016/j.tetlet.2010.01.087 | en_US |
| dc.identifier.issn | 00404039 | en_US |
| dc.identifier.other | 2-s2.0-76949103156 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/28750 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=76949103156&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Mukaiyama's reagent promoted C-N bond formation: a new method to synthesize 3-alkylquinazolin-4-ones | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=76949103156&origin=inward | en_US |