Publication: Isolated antibody to hepatitis B core antigen in HIV-1 infected patients and a pilot study of vaccination to determine the anamnestic response
| dc.contributor.author | Yongyuth Jongjirawisan | en_US |
| dc.contributor.author | Prayut Ungulkraiwit | en_US |
| dc.contributor.author | Somnuek Sungkanuparph | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Faculty of Medicine, Ramathibodi Hospital, Mahidol University | en_US |
| dc.date.accessioned | 2018-08-20T07:05:26Z | |
| dc.date.available | 2018-08-20T07:05:26Z | |
| dc.date.issued | 2006-12-01 | en_US |
| dc.description.abstract | Background: Isolated antibody to hepatitis B core antigen (anti-HBc) is frequently found in HIV-infected patients. The present study aimed to determine the prevalence and risk factors of isolated anti-HBc and the anamnestic response to hepatitis B vaccination in this population. Material and Method: HIV-infected patients who visited Ramathibodi Hospital in May 2006 were included to test hepatitis B serology. Subjects with isolated anti-HBc were given hepatitis B vaccine and tested for anti-HBs. Results: Of 140 patients, 28 (20%) had isolated anti-HBc. From multivariate analysis, IVDU (OR 30.8, p < 0.001) and anti-HCV seropositive (OR 6.7, p = 0.002) were independent risk factors for isolated anti-HBc. Two from 28 (7%) patients who received vaccine had a response to vaccination. Conclusion: Prevalence of isolated anti-HBc among Thai HIV-infected patients was 20%. Risk factors of isolated anti-HBc were IVDU and anti-HCV seropositive. Anamnestic response to hepatitis B vaccination was low. Further study with strategies to improve the response of vaccination is needed. | en_US |
| dc.identifier.citation | Journal of the Medical Association of Thailand. Vol.89, No.12 (2006), 2028-2034 | en_US |
| dc.identifier.issn | 01252208 | en_US |
| dc.identifier.issn | 01252208 | en_US |
| dc.identifier.other | 2-s2.0-33845624705 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/23426 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33845624705&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Isolated antibody to hepatitis B core antigen in HIV-1 infected patients and a pilot study of vaccination to determine the anamnestic response | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33845624705&origin=inward | en_US |