Journal of the Medical Association of Thailand. Vol.81, No.4 (1998), 300-303
Suggested Citation
Korntong Asvanich, Vichai Fugpholngam, Somboon Srimuang, Deja Tanphaichitra In Vitro Activity and Clinical Evaluation of Cefixime in Urinary Tract Infection. Journal of the Medical Association of Thailand. Vol.81, No.4 (1998), 300-303. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/18547
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In Vitro Activity and Clinical Evaluation of Cefixime in Urinary Tract Infection
Thirty-five women with uncomplicated acute lower urinary tract infections proven by significant pre-treatment bacteriuria (≥ 105CFU/ml) were treated with an oral dose of 100 mg cefixime twice a day for seven days. Thirty five patients included in this study were checked for response to treatment on the last day of therapy, 7-14 days and 4 weeks post therapy. The clinical response and bacterial eradication rate for cefixime were 91.4 per cent (32/35). The infecting organisms, E. coli and Proteus mirabilis, were inhibited at MIC90= 0.5 and ≤ 0.03 μg/ml, and MBC = 1 and 0.06 μg/ml respectively. No adverse events were found in this study.
