Publication: NephroCheck® Quality Test
Issued Date
2021-07-01
Resource Type
ISSN
14219735
02535068
02535068
Other identifier(s)
2-s2.0-85097814625
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Blood Purification. Vol.50, No.4-5 (2021), 489-491
Suggested Citation
Thummaporn Naorungroj, Ary Serpa Neto, Fumitaka Yanase, Intissar Bittar, Glenn M. Eastwood, Rinaldo Bellomo NephroCheck® Quality Test. Blood Purification. Vol.50, No.4-5 (2021), 489-491. doi:10.1159/000511727 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/78113
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Title
NephroCheck® Quality Test
Abstract
Background: The acute kidney injury (AKI) risk score helps detect moderate and severe AKI in the next 12-24 h. However, inappropriate urine collection may impact its results. Aim: The aim of this study was to evaluate the stability of NephroCheck® after urine storage at different temperatures. Methods: The urine sample was centrifuged and split into 3 tubes. One was tested as soon as possible by the laboratory. The other 2 samples were frozen at-20 and-80°C, and the NephroCheck® test was performed 8 weeks later. Results: The mean values of the AKI risk score were 1.19 ± 0.93, 1.15 ± 1.14, and 1.20 ± 1.11 (ng/mL)2/1,000 for fresh urine,-20, and-80°C, respectively (p = 0.70). Spearman's rank correlation for-20 and-80°C versus immediate processing was strong with a rho of 0.82 and 0.98, respectively. Conclusion: The AKI risk score was relatively stable. Urine could be collected without dry ice or liquid nitrogen and kept for up to 8 weeks with either-20 or-80°C freezing with stable NephroCheck® results.