Publication: 3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: Is 3-NPA in some plants produced by endophytes?
| dc.contributor.author | Porntep Chomcheon | en_US |
| dc.contributor.author | Suthep Wiyakrutta | en_US |
| dc.contributor.author | Nongluksna Sriubolmas | en_US |
| dc.contributor.author | Nattaya Ngamrojanavanich | en_US |
| dc.contributor.author | Duangnate Isarangkul | en_US |
| dc.contributor.author | Prasat Kittakoop | en_US |
| dc.contributor.other | Chulalongkorn University | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | The Institute of Science and Technology for Research and Development, Mahidol University | en_US |
| dc.contributor.other | Thailand National Center for Genetic Engineering and Biotechnology | en_US |
| dc.date.accessioned | 2018-06-21T08:09:01Z | |
| dc.date.available | 2018-06-21T08:09:01Z | |
| dc.date.issued | 2005-07-01 | en_US |
| dc.description.abstract | 3-Nitropropionic acid (3-NPA, 1) was found in extracts of several strains of endophytic fungi. 3-NPA (1) exhibited potent antimycobacterial activity with the minimum inhibition concentration of 3.3 μM, but was inactive against NCI-H187, BC, KB, and Vero cell lines. Endophytes were found to produce high levels of 3-NPA (1), and therefore 3-NPA (1) accumulated in certain plants may be produced by the associated endophytes. 3-NPA (1) may be used as a chemotaxonomic marker for endophytic fungi. The structure of 3-hydroxypropionic acid, a nematicidal agent, should be revised to 3-NPA (1). © 2005 American Chemical Society and American Society of Pharmacognosy. | en_US |
| dc.identifier.citation | Journal of Natural Products. Vol.68, No.7 (2005), 1103-1105 | en_US |
| dc.identifier.doi | 10.1021/np050036a | en_US |
| dc.identifier.issn | 01633864 | en_US |
| dc.identifier.other | 2-s2.0-23844439228 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/123456789/16328 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=23844439228&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Medicine | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | 3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: Is 3-NPA in some plants produced by endophytes? | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=23844439228&origin=inward | en_US |