Publication: The malaria parasite monitored by photoacoustic spectroscopy
| dc.contributor.author | D. Balasubramanian | en_US |
| dc.contributor.author | Ch Mohan Rao | en_US |
| dc.contributor.author | B. Panijpan | en_US |
| dc.contributor.other | Centre for Cellular and Molecular Biology india | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.date.accessioned | 2018-10-12T07:45:25Z | |
| dc.date.available | 2018-10-12T07:45:25Z | |
| dc.date.issued | 1984-01-01 | en_US |
| dc.description.abstract | Noninvasive photoacoustic spectroscopy was used to study the malaria parasites Plasmodium chabaudi and Plasmodium berghei, their pigment, and ferriprotoporphyrin IX, which is a by-product of the hemoglobin that the parasite ingests. The results indicate that the pigment consists of ferriprotophorphyrin self-aggregates and a noncovalent complex of ferriprotoporphyrin and protein. Spectra of chloroquine-treated parasites reveal in situ interaction between the drug and ferriprotoporphyrin. Chloroquine-resistant parasites, readily distinguishable by this method, appear to degrade hemoglobin only partially. | en_US |
| dc.identifier.citation | Science. Vol.223, No.4638 (1984), 828-830 | en_US |
| dc.identifier.doi | 10.1126/science.6695185 | en_US |
| dc.identifier.issn | 00368075 | en_US |
| dc.identifier.other | 2-s2.0-0021347929 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/123456789/30723 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021347929&origin=inward | en_US |
| dc.subject | Multidisciplinary | en_US |
| dc.title | The malaria parasite monitored by photoacoustic spectroscopy | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0021347929&origin=inward | en_US |