Publication:
Evaluation of T cells individually encapsulated within polyelectrolyte-coated gold nanorod shell after cryopreservation or −80 °C preservation

Issued Date

2020-03-23

Resource Type

Article

ISSN

1563535X
00914037

DOI

10.1080/00914037.2018.1563085

Other identifier(s)

2-s2.0-85060566433

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

International Journal of Polymeric Materials and Polymeric Biomaterials. Vol.69, No.5 (2020), 284-291

Suggested Citation

Porntida Wattanakull, Dakrong Pissuwan Evaluation of T cells individually encapsulated within polyelectrolyte-coated gold nanorod shell after cryopreservation or −80 °C preservation. International Journal of Polymeric Materials and Polymeric Biomaterials. Vol.69, No.5 (2020), 284-291. doi:10.1080/00914037.2018.1563085 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/49567

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Title

Evaluation of T cells individually encapsulated within polyelectrolyte-coated gold nanorod shell after cryopreservation or −80 °C preservation

Author(s)

Porntida Wattanakull
 Dakrong Pissuwan

Other Contributor(s)

Mahidol University

Abstract

© 2019, © 2019 Taylor & Francis Group, LLC. The encapsulation of single T cells has gained interest for cell-based therapy. We aimed to examine the biological activity of encapsulated cells after preservation under different conditions which were preservation at −80 °C and cryopreservation. Jurkat cells were encapsulated in polyelectrolytes (PAH or PSS) and in the layer of polyelectrolyte-coated gold nanorods (GNR-PSS). The encapsulation layer and the gold content could be detected after both types of preservation. The viability of encapsulated preserved Jurkat cells were in the range of ∼80–90%. TNF-α secretion was not induced. However, a significant induction of IL-6 levels was detected in encapsulated cells stored at −80 °C.

Keyword(s)

Chemical Engineering
 Chemistry
 Materials Science

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URI

https://repository.li.mahidol.ac.th/handle/123456789/49567

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Scopus 2020