Publication: Bioactive compounds from the seed fungus Menisporopsis theobromae BCC 3975
| dc.contributor.author | Maneekarn Chinworrungsee | en_US |
| dc.contributor.author | Prasat Kittakoop | en_US |
| dc.contributor.author | Janya Saenboonrueng | en_US |
| dc.contributor.author | Palangpon Kongsaeree | en_US |
| dc.contributor.author | Yodhathai Thebtaranonth | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | Thailand National Center for Genetic Engineering and Biotechnology | en_US |
| dc.date.accessioned | 2018-08-20T06:47:29Z | |
| dc.date.available | 2018-08-20T06:47:29Z | |
| dc.date.issued | 2006-10-01 | en_US |
| dc.description.abstract | Eight new compounds (2-9), together with a known dithiodiketopiperazine (1), were isolated from the seed fungus Menisporopsis theobromae BCC 3975. The structures of these substances were elucidated by analyses of spectroscopic data. Compounds 1 and 4 exhibited moderate cytotoxicity against BC-1 cell lines with IC50 values of 29.2 and 57.4 μM, respectively. Cytotoxicity of 1, 2, 4, and 9 against the NCI-H187 cell line showed respective IC 50 values of 22.9, 20.3, 1.8, and 56.6 μM. Compounds 2 and 4 exhibited antimalarial activity with IC50 values of 2.95 and 28.8 μM, respectively. Substances 1, 4, 7, 8, and 9 possessed weak antimycobacterial activity (MIC 154.8-952.3 μM), while compounds 2 and 3 showed potent antimycobacterial activity with respective MIC values of 1.24 and 7.14 μM. © 2006 American Chemical Society and American Society of Pharmacognosy. | en_US |
| dc.identifier.citation | Journal of Natural Products. Vol.69, No.10 (2006), 1404-1410 | en_US |
| dc.identifier.doi | 10.1021/np0601197 | en_US |
| dc.identifier.issn | 01633864 | en_US |
| dc.identifier.other | 2-s2.0-33845460633 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/22860 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33845460633&origin=inward | en_US |
| dc.subject | Agricultural and Biological Sciences | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Bioactive compounds from the seed fungus Menisporopsis theobromae BCC 3975 | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33845460633&origin=inward | en_US |