Publication: Suppressive effects of dichloromethane fraction from the Areca catechu nut on naloxone-precipitated morphine withdrawal in mice
dc.contributor.author | Ekkasit Kumarnsit | en_US |
dc.contributor.author | Niwat Keawpradub | en_US |
dc.contributor.author | Uraporn Vongvatcharanon | en_US |
dc.contributor.author | Kitja Sawangjaroen | en_US |
dc.contributor.author | Piyarat Govitrapong | en_US |
dc.contributor.other | Prince of Songkla University | en_US |
dc.contributor.other | The Institute of Science and Technology for Research and Development, Mahidol University | en_US |
dc.date.accessioned | 2018-06-21T08:33:45Z | |
dc.date.available | 2018-06-21T08:33:45Z | |
dc.date.issued | 2005-09-01 | en_US |
dc.description.abstract | In the present study, we investigated the effect of the dichloromethane fraction from Areca catechu nut on the severity of naloxone-precipitated morphine withdrawal in morphine-dependent mice. A single intraperitoneal injection of dichloromethane fraction at dose of 125 and 175 mg/kg significantly delayed the onset of withdrawal jumping behavior in a concentration-dependent manner compared to that of saline controls. The dichloromethane fractions also significantly decreased jumping numbers and faecal and urinary excretions during the withdrawal period. © 2005 Elsevier B.V. All rights reserved. | en_US |
dc.identifier.citation | Fitoterapia. Vol.76, No.6 (2005), 534-539 | en_US |
dc.identifier.doi | 10.1016/j.fitote.2005.04.015 | en_US |
dc.identifier.issn | 0367326X | en_US |
dc.identifier.other | 2-s2.0-26944494633 | en_US |
dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/17160 | |
dc.rights | Mahidol University | en_US |
dc.rights.holder | SCOPUS | en_US |
dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=26944494633&origin=inward | en_US |
dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
dc.title | Suppressive effects of dichloromethane fraction from the Areca catechu nut on naloxone-precipitated morphine withdrawal in mice | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | |
mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=26944494633&origin=inward | en_US |