Publication: Identification of a novel HIV type 1 CRF01_AE cytotoxic T lymphocyte (CTL) epitope restricted by an HLA-Cw0602 allele and a novel HLA-A0206/peptide restriction
dc.contributor.author | Wannee Kantakamalakul | en_US |
dc.contributor.author | Mark De Souza | en_US |
dc.contributor.author | Sasitorn Bejrachandra | en_US |
dc.contributor.author | Silawun Ampol | en_US |
dc.contributor.author | Josephine Cox | en_US |
dc.contributor.author | Ruengpung Sutthent | en_US |
dc.contributor.other | Mahidol University | en_US |
dc.contributor.other | Armed Forces Research Institute of Medical Sciences, Thailand | en_US |
dc.contributor.other | U.S. Military HIV Research Program | en_US |
dc.date.accessioned | 2018-08-20T06:59:49Z | |
dc.date.available | 2018-08-20T06:59:49Z | |
dc.date.issued | 2006-12-01 | en_US |
dc.description.abstract | This report describes specific T cell responses to HIV-1 CRF01_AE Env and A Gag peptides in 20 HIV-1 CRF01_AE-infected Thai individuals using an interferon-γ (IFN-γ) enzyme-linked immunospot (ELISpot) assay. Twenty-six potentially novel HLA class I-restricted CD8+ T cell epitopes were identified in 14/20 subjects. Fine mapping analysis using the chromium release cytotoxic T lymphocyte (CTL) assay revealed a novel HLA-Cw0602 restricted epitope of HIV-1 CRF01_AE Env (NAKTIIVHL) and a previously identified HIV-1 A Gag epitope (ATLEEMMTA) with a novel HLA-A0206 restriction. © Mary Ann Liebert, Inc. | en_US |
dc.identifier.citation | AIDS Research and Human Retroviruses. Vol.22, No.12 (2006), 1271-1282 | en_US |
dc.identifier.doi | 10.1089/aid.2006.22.1271 | en_US |
dc.identifier.issn | 08892229 | en_US |
dc.identifier.other | 2-s2.0-33846191162 | en_US |
dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/23278 | |
dc.rights | Mahidol University | en_US |
dc.rights.holder | SCOPUS | en_US |
dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846191162&origin=inward | en_US |
dc.subject | Immunology and Microbiology | en_US |
dc.subject | Medicine | en_US |
dc.title | Identification of a novel HIV type 1 CRF01_AE cytotoxic T lymphocyte (CTL) epitope restricted by an HLA-Cw0602 allele and a novel HLA-A0206/peptide restriction | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | |
mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33846191162&origin=inward | en_US |