Publication:
IgG Antibody Responses Are Preferential Compared with IgM for Use as Serological Markers for Detecting Recent Exposure to Plasmodium vivax Infection

Simple item page
dc.contributor.authorRhea J. Longleyen_US
dc.contributor.authorMichael T. Whiteen_US
dc.contributor.authorJessica Brewsteren_US
dc.contributor.authorZoe S.J. Liuen_US
dc.contributor.authorCaitlin Bourkeen_US
dc.contributor.authorEizo Takashimaen_US
dc.contributor.authorMatthias Harbersen_US
dc.contributor.authorWai Hong Thamen_US
dc.contributor.authorJulie Healeren_US
dc.contributor.authorChetan E. Chitnisen_US
dc.contributor.authorWuelton Monteiroen_US
dc.contributor.authorMarcus Lacerdaen_US
dc.contributor.authorJetsumon Sattabongkoten_US
dc.contributor.authorTakafumi Tsuboien_US
dc.contributor.authorIvo Muelleren_US
dc.contributor.otherFaculty of Tropical Medicine, Mahidol Universityen_US
dc.contributor.otherWalter and Eliza Hall Institute of Medical Researchen_US
dc.contributor.otherUniversity of Melbourneen_US
dc.contributor.otherFiocruz Amazôniaen_US
dc.contributor.otherRikenen_US
dc.contributor.otherUniversidade do Estado do Amazonasen_US
dc.contributor.otherEhime Universityen_US
dc.contributor.otherInstitut Pasteur, Parisen_US
dc.contributor.otherFundação de Medicina Tropical Dr. Heitor Vieira Douradoen_US
dc.date.accessioned2022-08-04T09:21:30Z
dc.date.available2022-08-04T09:21:30Z
dc.date.issued2021-06-01en_US
dc.description.abstractTo achieve malaria elimination, new tools are required to explicitly target Plasmodium vivax. Recently, a novel panel of P. vivax proteins were identified and validated as serological markers for detecting recent exposure to P. vivax within the last 9 months. In order to improve the sensitivity and specificity of these markers, immunoglobulin M (IgM) in addition to immunoglobulin G (IgG) antibody responses were compared with a down-selected panel of 20 P. vivax proteins. IgM was tested using archival plasma samples from observational cohort studies conducted in malaria-endemic regions of Thailand and Brazil. IgM responses to these proteins generally had poorer classification performance than IgG.en_US
dc.identifier.citationOpen Forum Infectious Diseases. Vol.8, No.6 (2021)en_US
dc.identifier.doi10.1093/ofid/ofab228en_US
dc.identifier.issn23288957en_US
dc.identifier.other2-s2.0-85118669660en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/78128
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85118669660&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleIgG Antibody Responses Are Preferential Compared with IgM for Use as Serological Markers for Detecting Recent Exposure to Plasmodium vivax Infectionen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85118669660&origin=inwarden_US

Files

Collections

Scopus 2021