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Detection of herpes simplex virus type 2 Bgl II N fragment in paraffin-embedded cervical tissue sections using nested polymerase chain reaction

dc.contributor.authorViraphong Lulitanonden_US
dc.contributor.authorWasun Chantratitaen_US
dc.contributor.authorKamthorn Thammapraserten_US
dc.contributor.authorKanchana Nimmanahaemindaen_US
dc.contributor.authorPornchai Matangkasombuten_US
dc.contributor.authorChalobon Yoosooken_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherFaculty of Assoc. Medical Sciencesen_US
dc.contributor.otherChiang Mai Universityen_US
dc.date.accessioned2018-02-27T04:25:41Z
dc.date.available2018-02-27T04:25:41Z
dc.date.issued1994-01-01en_US
dc.description.abstractTo study the presence of transforming sequence Bgl II N of HSV-2 in cervical cancer tissues, we developed the nested polymerase chain reaction (PCR) for detecting such a sequence in paraffinembedded cervical tissue sections. Samples derived from 46 patients with premalignant and malignant lesions were tested. The sequence was found in 20-25% of total cases tested but not observed in any of the normal healthy controls. This study also indicates that for the detection of HSV-2 Bgl II N sequence in cervical tissue, the nested PCR may be more reliable than the in situ hybridization method. © 1994 Academic Press.en_US
dc.identifier.citationMolecular and Cellular Probes. Vol.8, No.6 (1994), 441-447en_US
dc.identifier.doi10.1006/mcpr.1994.1063en_US
dc.identifier.issn08908508en_US
dc.identifier.other2-s2.0-0028566611en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/9534
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0028566611&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleDetection of herpes simplex virus type 2 Bgl II N fragment in paraffin-embedded cervical tissue sections using nested polymerase chain reactionen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0028566611&origin=inwarden_US

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