Publication: Beta-blocker and its neuropsychiatric effects
2
Issued Date
2020-01-01
Resource Type
ISSN
19054637
01254685
01254685
Other identifier(s)
2-s2.0-85086670699
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Thai Journal of Pharmaceutical Sciences. Vol.44, No.2 (2020), 117-123
Suggested Citation
Ploylarp Lertvipapath, Wikrom Warunyuwong Beta-blocker and its neuropsychiatric effects. Thai Journal of Pharmaceutical Sciences. Vol.44, No.2 (2020), 117-123. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/58363
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Beta-blocker and its neuropsychiatric effects
Author(s)
Other Contributor(s)
Abstract
© 2020, Faculty of Pharmaceutical Sciences, Chulalongkorn University. All rights reserved. Norepinephrine from locus coeruleus plays roles in memory processes and behavioral controls. Locus coeruleus change is found in the primary neurodegenerative disease. The disruption of this central adrenergic pathway could contribute to neuropsychiatric symptoms. β-blockers which are indicated in many conditions both cardiovascular and non-cardiovascular diseases directly interrupt the adrenergic pathway. Their peripheral effects are well understood, but the neuropsychiatric effects are still questionable. The previous evidence postulated that the medication may cause behavioral impairment. This review focused on neuropsychiatric effects which were related to β-blockers and their underlying mechanisms. These neuropharmacologic properties should be necessary for health-care personnel to be aware of the side effects and closely take care of the patients who taking β-blockers.