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Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.

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dc.contributor.authorFärnert, Annaen_US
dc.contributor.authorUrsing, Johanen_US
dc.contributor.authorTolfvenstam, Thomasen_US
dc.contributor.authorRono, Joseaen_US
dc.contributor.authorKarlsson, Lillemoren_US
dc.contributor.authorSparrelid, Eldaen_US
dc.contributor.authorLindegårdh, Niklasen_US
dc.contributor.correspondenceanna.farnert@ki.seen_US
dc.contributor.otherMahidol University. Faculty of Tropical Medicine. Mahidol-Oxford Tropical Medicine Research Unit.en_US
dc.date.accessioned2014-06-30T07:18:24Z
dc.date.accessioned2016-09-21T03:24:29Z
dc.date.available2014-06-30T07:18:24Z
dc.date.available2016-09-21T03:24:29Z
dc.date.copyright2012
dc.date.created2014-06-25
dc.date.issued2012-05-25
dc.description.abstractArtemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment.en_US
dc.identifier.citationFärnert A, Ursing J, Tolfvenstam T, Rono J, Karlsson L, Sparrelid E, et al. Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. Malar J. 2012 May 25;11:176.en_US
dc.identifier.doi10.1186/1475-2875-11-176.
dc.identifier.issn1475-2875 (electronic)
dc.identifier.issn1475-2875 (Linking)
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/666
dc.language.isoengen_US
dc.rightsMahidol Universityen_US
dc.rights.holderBioMed Centralen_US
dc.subjectArtemisninen_US
dc.subjectLumefantrineen_US
dc.subjectMalariaen_US
dc.subjectnon-immuneen_US
dc.subjectP. falciparumen_US
dc.subjectOpen Access articleen_US
dc.titleArtemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.en_US
dcterms.dateAccepted2012-05-25
dspace.entity.typePublication
mods.location.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416680/pdf/1475-2875-11-176.pdf

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