Publication:
Genomic characterization of carbapenemase-producing klebsiella pneumoniae with chromosomally carried bla <inf>NDM-1</inf>

dc.contributor.authorNoriko Sakamotoen_US
dc.contributor.authorYukihiro Akedaen_US
dc.contributor.authorYo Sugawaraen_US
dc.contributor.authorDan Takeuchien_US
dc.contributor.authorDaisuke Motookaen_US
dc.contributor.authorNorihisa Yamamotoen_US
dc.contributor.authorWarawut Laolerden_US
dc.contributor.authorPitak Santaniranden_US
dc.contributor.authorShigeyuki Hamadaen_US
dc.contributor.otherOsaka Universityen_US
dc.contributor.otherHandai Byoinen_US
dc.contributor.otherFaculty of Medicine, Ramathibodi Hospital, Mahidol Universityen_US
dc.date.accessioned2019-08-23T11:34:01Z
dc.date.available2019-08-23T11:34:01Z
dc.date.issued2018-12-01en_US
dc.description.abstract© 2018 American Society for Microbiology. All Rights Reserved. We report here Klebsiella pneumoniae strains carrying chromosomal bla NDM-1 in Thailand. The genomes of these two isolates include a 160-kbp insertion containing bla NDM-1 , which is almost identical to that in the IncHI1B-like plasmid. Further analysis indicated that IS5-mediated intermolecular transposition and Tn3 transposase-mediated homologous recombination resulted in the integration of bla NDM-1 into the chromosome from an IncHI1B-like plasmid. The spread of this type of carbapenem-resistant Enterobacteriaceae may threaten public health and warrants further monitoring.en_US
dc.identifier.citationAntimicrobial Agents and Chemotherapy. Vol.62, No.12 (2018)en_US
dc.identifier.doi10.1128/AAC.01520-18en_US
dc.identifier.issn10986596en_US
dc.identifier.issn00664804en_US
dc.identifier.other2-s2.0-85057185517en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/46157
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057185517&origin=inwarden_US
dc.subjectMedicineen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleGenomic characterization of carbapenemase-producing klebsiella pneumoniae with chromosomally carried bla <inf>NDM-1</inf>en_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85057185517&origin=inwarden_US

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