Publication: Platelet function tests in thalassemic children.
Issued Date
1987-12-01
Resource Type
ISSN
05476844
Other identifier(s)
2-s2.0-0023474259
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Mahidol University
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SCOPUS
Bibliographic Citation
Birth defects original article series. Vol.23, No.5 A (1987), 395-401
Suggested Citation
P. Isarangkura, P. Pintadit, P. Hathirat, W. Sasanakul Platelet function tests in thalassemic children.. Birth defects original article series. Vol.23, No.5 A (1987), 395-401. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15301
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Title
Platelet function tests in thalassemic children.
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Abstract
Platelet changes in thalassemia included prolongation of bleeding time (30%), thrombocytosis (29%), decreased platelet retention (79%), and normal PF3 release. Platelet aggregation was found to be hyperaggregation in 50%, normal in 22%, and hypoaggregation in 28% of the studied patients. Platelet changes in thalassemia can be hyper-, normal, or hypofunction. The changes are likely to be related to many factors, particularly to the progress of the disease. Platelet hypoaggregation may lead to a bleeding problem. Platelet hyperaggregation and thrombocytosis were prominent in the splenectomized patients and/or the severely anemic group; antiplatelet drugs may be indicated in these patients.
