Publication: Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells
| dc.contributor.author | Amaraporn Wongrakpanich | en_US |
| dc.contributor.author | Imali A. Mudunkotuwa | en_US |
| dc.contributor.author | Sean M. Geary | en_US |
| dc.contributor.author | Angie S. Morris | en_US |
| dc.contributor.author | Kranti A. Mapuskar | en_US |
| dc.contributor.author | Douglas R. Spitz | en_US |
| dc.contributor.author | Vicki H. Grassian | en_US |
| dc.contributor.author | Aliasger K. Salem | en_US |
| dc.contributor.other | University of Iowa | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | University of Iowa Carver College of Medicine | en_US |
| dc.contributor.other | Scripps Institution of Oceanography | en_US |
| dc.date.accessioned | 2018-12-11T02:54:51Z | |
| dc.date.accessioned | 2019-03-14T08:01:29Z | |
| dc.date.available | 2018-12-11T02:54:51Z | |
| dc.date.available | 2019-03-14T08:01:29Z | |
| dc.date.issued | 2016-01-01 | en_US |
| dc.description.abstract | © 2016 The Royal Society of Chemistry. The increasing use of copper oxide (CuO) nanoparticles (NPs) in medicine and industry demands an understanding of their potential toxicities. In this study, we compared the in vitro cytotoxicity of CuO NPs of two distinct sizes (4 and 24 nm) using the A549 human lung cell line. Despite possessing similar surface and core oxide compositions, 24 nm CuO NPs were significantly more cytotoxic than 4 nm CuO NPs. The difference in size may have affected the rate of entry of NPs into the cell, potentially influencing the amount of intracellular dissolution of Cu2+and causing a differential impact on cytotoxicity. | en_US |
| dc.identifier.citation | Environmental Science: Nano. Vol.3, No.2 (2016), 365-374 | en_US |
| dc.identifier.doi | 10.1039/c5en00271k | en_US |
| dc.identifier.issn | 20518161 | en_US |
| dc.identifier.issn | 20518153 | en_US |
| dc.identifier.other | 2-s2.0-84964612040 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/40623 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84964612040&origin=inward | en_US |
| dc.subject | Environmental Science | en_US |
| dc.subject | Materials Science | en_US |
| dc.title | Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84964612040&origin=inward | en_US |