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Establishment of a rabbit induced pluripotent stem cell (RbiPSC) line using lentiviral delivery of human pluripotency factors

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dc.contributor.authorZsuzsanna Táncosen_US
dc.contributor.authorCsilla Nemesen_US
dc.contributor.authorEszter Vargaen_US
dc.contributor.authorIstván Bocken_US
dc.contributor.authorSasitorn Rungarunlerten_US
dc.contributor.authorTheerawat Tharasaniten_US
dc.contributor.authorMongkol Techakumphuen_US
dc.contributor.authorJulianna Koboláken_US
dc.contributor.authorAndrás Dinnyésen_US
dc.contributor.otherSzent István Egyetemen_US
dc.contributor.otherBioTalentum Ltd.en_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherChulalongkorn Universityen_US
dc.contributor.otherUtrecht Universityen_US
dc.date.accessioned2018-12-21T06:49:30Z
dc.date.accessioned2019-03-14T08:02:54Z
dc.date.available2018-12-21T06:49:30Z
dc.date.available2019-03-14T08:02:54Z
dc.date.issued2017-05-01en_US
dc.description.abstract© 2017 The Authors Rabbit Embryonic Fibroblast (RbEF) cells (from Hycole hybrid rabbit foetus) were reprogrammed by lentiviral delivery of a self-silencing hOKSM polycistronic vector. The pluripotency of the newly generated RbiPSC was verified by the expression of pluripotency-associated markers and by in vitro spontaneous differentiation towards the 3 germ layers. Furthermore, the spontaneous differentiation potential of the iPSC was also tested in vivo by teratoma assay. The iPSC line showed normal karyotype. The advantages of using RbiPSC are the easy access to primary material and the possibility to study the efficacy and safety of the iPSC-based therapies on a non-rodent animal model.en_US
dc.identifier.citationStem Cell Research. Vol.21, (2017), 16-18en_US
dc.identifier.doi10.1016/j.scr.2017.03.010en_US
dc.identifier.issn18767753en_US
dc.identifier.issn18735061en_US
dc.identifier.other2-s2.0-85015993999en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/41885
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85015993999&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleEstablishment of a rabbit induced pluripotent stem cell (RbiPSC) line using lentiviral delivery of human pluripotency factorsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85015993999&origin=inwarden_US

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