Sensitization profile of Thai children with fish allergy
1
Issued Date
2025-01-01
Resource Type
ISSN
03010546
eISSN
15781267
Scopus ID
2-s2.0-85219542207
Journal Title
Allergologia et Immunopathologia
Volume
53
Issue
2
Start Page
108
End Page
112
Rights Holder(s)
SCOPUS
Bibliographic Citation
Allergologia et Immunopathologia Vol.53 No.2 (2025) , 108-112
Suggested Citation
Tangvalelerd S., Piboonpocanun S., Raungsirarak U., Sirichuwong M., Vichyanond P., Pacharn P. Sensitization profile of Thai children with fish allergy. Allergologia et Immunopathologia Vol.53 No.2 (2025) , 108-112. 112. doi:10.15586/aei.v53i2.1209 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/106638
Title
Sensitization profile of Thai children with fish allergy
Corresponding Author(s)
Other Contributor(s)
Abstract
Introduction: Fish allergies are common food allergies, and in Thailand, the prevalence of fish allergies in children ranges from 0.29% to 1.1%. Common fish allergens include parvalbumin, enolase, and aldolase. Method: This cross-sectional study included children with immunoglobulin E (IgE)-mediated fish allergies. The diagnosis was based on clinical history with a positive skin prick test (SPT) and/or specific IgE (sIgE). Serum IgE binding profiles to allergens in fish extracts were analyzed. Result: Eleven children, with a median age of 3 years, were recruited; the median age of onset was 1.25 years. Cutaneous symptoms were the most frequent clinical manifestation (63.6%). Tilapia and catfish were the most common triggers. All participants showed positive SPT and/or sIgE results for fish species. The immunoblot analysis revealed IgE binding to 40–50 kDa protein in all participants, while only seven participants (63.6%) showed IgE binding to the 11 kDa protein. Conclusion: Tilapia and catfish are the most common triggers of fish allergies in Thai children. The 40–50 kDa proteins were identified as a major fish allergen in tested cohort.