Antimicrobial Peptides: Could it be an Alternative to Antibiotics in Boar Semen Extender?
1
Issued Date
2025-01-01
Resource Type
ISSN
01256491
Scopus ID
2-s2.0-85219687966
Journal Title
Thai Journal of Veterinary Medicine
Volume
55
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
Thai Journal of Veterinary Medicine Vol.55 No.1 (2025)
Suggested Citation
Keeratikunakorn K., Chanapiwat P., Kaeoket K. Antimicrobial Peptides: Could it be an Alternative to Antibiotics in Boar Semen Extender?. Thai Journal of Veterinary Medicine Vol.55 No.1 (2025). doi:10.56808/2985-1130.3777 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/106647
Title
Antimicrobial Peptides: Could it be an Alternative to Antibiotics in Boar Semen Extender?
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Abstract
Since antimicrobial resistance is a major global issue, "One Health" approaches such as the use of antimicrobial peptides (AMPs) were developed as an alternative antimicrobial agent which might be used in pig farms to reduce or replace non-rational antibiotics usage. Although AMPs showed several effects on antimicrobial agents, including against bacteria, fungi, protozoa, and viruses, as well as effects on host immunity, the ability to eliminate bacteria while providing the minimum amount of damage to the host cell is a particularly outstanding characteristic. Two major mechanisms of action of AMPs include membrane-active and intracellular-active. During the past decade, many AMPs have been tested for a replacement of antibiotics in boar semen extenders. Many studies reported the potential for using AMPs, whether as single or cocktail AMPs; however, their antibacterial effectiveness depends on the concentration and incubation time. Using AMPs also showed promising results on boar sperm quality and fertility tests on the pig farm. This review article discusses the use of AMPs as antibacterial agents for supplementation in boar semen extenders and provides future perspectives on the development of AMPs and how to use them properly.