Cryptococcal endophthalmitis in a patient with malignancy: A case report and literature review
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Issued Date
2025-06-01
Resource Type
ISSN
22117539
Scopus ID
2-s2.0-105003133426
Journal Title
Medical Mycology Case Reports
Volume
48
Rights Holder(s)
SCOPUS
Bibliographic Citation
Medical Mycology Case Reports Vol.48 (2025)
Suggested Citation
Phaopraphat K., Sirijatuphat R. Cryptococcal endophthalmitis in a patient with malignancy: A case report and literature review. Medical Mycology Case Reports Vol.48 (2025). doi:10.1016/j.mmcr.2025.100703 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/109875
Title
Cryptococcal endophthalmitis in a patient with malignancy: A case report and literature review
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Author's Affiliation
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Abstract
Cryptococcal endophthalmitis is a rare manifestation of cryptococcal infection, typically occurring in immunocompromised patients. In this case report, we present a 50-year-old female with advanced-stage lung cancer with multiple metastases presenting with blurred vision for 10 days. A diagnostic pars plana vitrectomy revealed Cryptococcus neoformans in the vitreous. She was treated with systemic amphotericin B and flucytosine, followed by fluconazole for consolidation and maintenance, along with intravitreal amphotericin B and voriconazole injections. Her visual acuity improved from counting fingers at 2 feet to 3/60, with a pinhole correction of 6/18 after 10 months of treatment.