Tryptophan-Derived Polynorbornene–Multiwalled Carbon Nanotube Fluorescent Chemosensors for Cu2+Detection and Thiol Discrimination
Issued Date
2025-08-22
Resource Type
eISSN
26376105
Scopus ID
2-s2.0-105014186620
Journal Title
ACS Applied Polymer Materials
Volume
7
Issue
16
Start Page
10465
End Page
10481
Rights Holder(s)
SCOPUS
Bibliographic Citation
ACS Applied Polymer Materials Vol.7 No.16 (2025) , 10465-10481
Suggested Citation
Sutthasupa S., Wangngae S., Khunpiluek T., Thisan S., Jarisarapurin W., Kumphune S., Pankaew A., Vettavong T., Thepmongkorn W., Chaiwat W. Tryptophan-Derived Polynorbornene–Multiwalled Carbon Nanotube Fluorescent Chemosensors for Cu2+Detection and Thiol Discrimination. ACS Applied Polymer Materials Vol.7 No.16 (2025) , 10465-10481. 10481. doi:10.1021/acsapm.5c01243 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/111910
Title
Tryptophan-Derived Polynorbornene–Multiwalled Carbon Nanotube Fluorescent Chemosensors for Cu2+Detection and Thiol Discrimination
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Abstract
Polymer-carbon nanotube hybrids were synthesized via the ring-opening metathesis polymerization (ROMP) of a tryptophan-derived polynorbornene and norbornene-functionalized multiwalled carbon nanotubes (MWCNTs) using a Grubbs M31 catalyst. Successful copolymerization was confirmed by proton nuclear magnetic resonance, transmission electron microscopy, thermogravimetric analysis, and Raman spectroscopy, ensuring the nanostructural integrity. The hybrids functioned as fluorescent chemosensors, exhibiting strong quenching in response to Cu<sup>2+</sup>, Fe<sup>3+</sup>, Pb<sup>2+</sup>, and Zn<sup>2+</sup>, with MWCNTs enhancing the metal ion adsorption. They achieved detection limits of 16.23–47.40 μM for Cu<sup>2+</sup>and Fe<sup>3+</sup>and displayed selective fluorescence recovery with cysteine over homocysteine and glutathione. Detection in human serum validated their efficacy in complex biological media, with cytotoxicity and cellular uptake studies confirming biocompatibility, suggesting the potential for further in vivo application with safety. These results demonstrate the potential of ROMP-based polymer–nanotube hybrids for biomedical and environmental sensing applications.