Chia seed mucilage biosorbent synergism with hydrophobic iron (III)-natural phenolic nanoparticles for dispersive solid-phase extraction of tetracycline residues in milk and honey samples before HPLC analysis
Issued Date
2025-12-01
Resource Type
ISSN
03088146
eISSN
18737072
Scopus ID
2-s2.0-105015144607
Journal Title
Food Chemistry
Volume
494
Rights Holder(s)
SCOPUS
Bibliographic Citation
Food Chemistry Vol.494 (2025)
Suggested Citation
Nakhonchai N., Ponhong K., Sweedler J.V., Lee C.Y., Supharoek S.a. Chia seed mucilage biosorbent synergism with hydrophobic iron (III)-natural phenolic nanoparticles for dispersive solid-phase extraction of tetracycline residues in milk and honey samples before HPLC analysis. Food Chemistry Vol.494 (2025). doi:10.1016/j.foodchem.2025.146239 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/112024
Title
Chia seed mucilage biosorbent synergism with hydrophobic iron (III)-natural phenolic nanoparticles for dispersive solid-phase extraction of tetracycline residues in milk and honey samples before HPLC analysis
Corresponding Author(s)
Other Contributor(s)
Abstract
This study utilized the synergistic effectiveness of chia seed mucilage and iron (III)-natural phenolic nanoparticles as biosorbents for the first time in the dispersive solid-phase extraction (DSPE) of oxytetracycline, tetracycline, chlortetracycline, and doxycycline followed by HPLC-UV quantification. An in-situ iron (III)-natural phenolic solid adsorbent was created using natural phenolics found in the copper pod tree bark. An ultrasonic-assisted extraction was performed to enhance the extraction efficiency of DSPE-based biosorbents. Excellent linearity with R<sup>2</sup> greater than 0.9957 was achieved, with detection limits between 0.7 and 2.0 μg L<sup>−1</sup> for milk, 2.5 and 7.5 μg kg<sup>−1</sup> for honey, and precisions below 9.1 %. The DSPE-based biosorbent was effectively applied to quantify tetracycline residues in milk and honey samples, yielding recoveries from 72.1 to 116.2 %. This method showed potential as an alternative simple, low-cost, eco-friendly, biodegradable, and reusable biosorbent to determine tetracycline residues in food.