Naturally Occurring Peripheral T-cell Lymphoma Not Otherwise Specified (PTCL-NOS) with Systemic Dissemination in a Beagle
Issued Date
2022-03-01
Resource Type
ISSN
01256491
Scopus ID
2-s2.0-105016344089
Journal Title
Thai Journal of Veterinary Medicine
Volume
52
Issue
1
Start Page
217
End Page
222
Rights Holder(s)
SCOPUS
Bibliographic Citation
Thai Journal of Veterinary Medicine Vol.52 No.1 (2022) , 217-222
Suggested Citation
Nganthavee P., Channgam P., Kasantikul T., Arya N., Sirivisoot S., Thaiwong T., Millman Z., Osathanon R. Naturally Occurring Peripheral T-cell Lymphoma Not Otherwise Specified (PTCL-NOS) with Systemic Dissemination in a Beagle. Thai Journal of Veterinary Medicine Vol.52 No.1 (2022) , 217-222. 222. doi:10.14456/tjvm.2022.24 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/112287
Title
Naturally Occurring Peripheral T-cell Lymphoma Not Otherwise Specified (PTCL-NOS) with Systemic Dissemination in a Beagle
Corresponding Author(s)
Other Contributor(s)
Abstract
A 6-year-old intact female Beagle dog presented with acute vomiting. Abdominal ultrasound showed abdominal lymphadenopathy, ascites and a hyperechoic mass within the pancreas. Thoracic radiographs and echocardiography revealed cardiomegaly with pericardial effusion. The dog died following rapid deterioration and a subsequent necropsy revealed a multilobulated white-to-tan mass within the pancreas, attaching to the omentum, stomach and left adrenal gland. The heart was enlarged and infiltrated by similar coalescing off-white irregular masses. Histologically, the masses consisted of infiltrative sheets of large T lymphocytes replacing the normal architecture of the heart along with the lymph nodes, pancreas, stomach, omentum, left adrenal gland, right ovary, heart, liver, gall bladder as well as the lungs and eyes. Based on histomorphology and immunophenotyping, this case was diagnosed as peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) with systemic dissemination to unusual sites including the heart.