Key Predictors of Adherence to a Mobile Health App for Managing Chronic Spontaneous Urticaria
Issued Date
2025-11-01
Resource Type
eISSN
20457022
Scopus ID
2-s2.0-105021538480
Journal Title
Clinical and Translational Allergy
Volume
15
Issue
11
Rights Holder(s)
SCOPUS
Bibliographic Citation
Clinical and Translational Allergy Vol.15 No.11 (2025)
Suggested Citation
Viegas H., Sousa-Pinto B., Vieira R.J., Ramanauskaite A., Witte-Händel E., Gimenez-Arnau A., Guillet C., Salvador Parisi C.A., Katelaris C., Fomina D., Larenas-Linnemann D., Sánchez J., Garcia E., Lima H., Kaidashev I., Nasr I., Canales I.O., Cherrez-Ojeda I., Bousquet J., Bernstein J.A., Peter J., Larco Sousa J.I., Kulthanan K., Weller K., Godse K., Rutkowski K., Lapina L., Bouillet L., Ensina L.F., Gonçalo M., Staevska M., Al-Nesf M.A.Y., Magerl M., Metz M., van Doorn M., Castor M.A., Khoshkhui M., Makris M., Hide M., Abuzakouk M., Al-Ahmad M., Türk M., Teovska Mitrevska N., Conlon N., Nojarov N., Kolkhir P., Li P., Ali R.M., Arnaout R., Asero R., Altrichter S., Thomsen S.F., Ye Y.M., Brzoza Z., Zhao Z., Zuberbier T., Siebenhaar F., Kocatürk E., Neisinger S. Key Predictors of Adherence to a Mobile Health App for Managing Chronic Spontaneous Urticaria. Clinical and Translational Allergy Vol.15 No.11 (2025). doi:10.1002/clt2.70110 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/113152
Title
Key Predictors of Adherence to a Mobile Health App for Managing Chronic Spontaneous Urticaria
Author(s)
Viegas H.
Sousa-Pinto B.
Vieira R.J.
Ramanauskaite A.
Witte-Händel E.
Gimenez-Arnau A.
Guillet C.
Salvador Parisi C.A.
Katelaris C.
Fomina D.
Larenas-Linnemann D.
Sánchez J.
Garcia E.
Lima H.
Kaidashev I.
Nasr I.
Canales I.O.
Cherrez-Ojeda I.
Bousquet J.
Bernstein J.A.
Peter J.
Larco Sousa J.I.
Kulthanan K.
Weller K.
Godse K.
Rutkowski K.
Lapina L.
Bouillet L.
Ensina L.F.
Gonçalo M.
Staevska M.
Al-Nesf M.A.Y.
Magerl M.
Metz M.
van Doorn M.
Castor M.A.
Khoshkhui M.
Makris M.
Hide M.
Abuzakouk M.
Al-Ahmad M.
Türk M.
Teovska Mitrevska N.
Conlon N.
Nojarov N.
Kolkhir P.
Li P.
Ali R.M.
Arnaout R.
Asero R.
Altrichter S.
Thomsen S.F.
Ye Y.M.
Brzoza Z.
Zhao Z.
Zuberbier T.
Siebenhaar F.
Kocatürk E.
Neisinger S.
Sousa-Pinto B.
Vieira R.J.
Ramanauskaite A.
Witte-Händel E.
Gimenez-Arnau A.
Guillet C.
Salvador Parisi C.A.
Katelaris C.
Fomina D.
Larenas-Linnemann D.
Sánchez J.
Garcia E.
Lima H.
Kaidashev I.
Nasr I.
Canales I.O.
Cherrez-Ojeda I.
Bousquet J.
Bernstein J.A.
Peter J.
Larco Sousa J.I.
Kulthanan K.
Weller K.
Godse K.
Rutkowski K.
Lapina L.
Bouillet L.
Ensina L.F.
Gonçalo M.
Staevska M.
Al-Nesf M.A.Y.
Magerl M.
Metz M.
van Doorn M.
Castor M.A.
Khoshkhui M.
Makris M.
Hide M.
Abuzakouk M.
Al-Ahmad M.
Türk M.
Teovska Mitrevska N.
Conlon N.
Nojarov N.
Kolkhir P.
Li P.
Ali R.M.
Arnaout R.
Asero R.
Altrichter S.
Thomsen S.F.
Ye Y.M.
Brzoza Z.
Zhao Z.
Zuberbier T.
Siebenhaar F.
Kocatürk E.
Neisinger S.
Author's Affiliation
McMaster University
The University of Hong Kong
Charité – Universitätsmedizin Berlin
Erasmus MC
National and Kapodistrian University of Athens
Hiroshima University
Universidade Federal de São Paulo
Pontificia Universidad Católica de Chile
University of Cincinnati College of Medicine
Western Sydney University
Sechenov First Moscow State Medical University
Universitat Pompeu Fabra Barcelona
Johannes Kepler University Linz
Mashhad University of Medical Sciences
Guy's and St Thomas' NHS Foundation Trust
Kuwait University
Universidad de Antioquia
Centre Hospitalier Universitaire de Grenoble
Medical University of Sofia
Universidad de Los Andes, Colombia
Peking University First Hospital
Faculdade de Medicina da Universidade do Porto (FMUP)
Siriraj Hospital
Bispebjerg Hospital
King Faisal Specialist Hospital & Research Centre
Ajou University School of Medicine
Groote Schuur Hospital
Bahçeşehir Üniversitesi
Universidade de Coimbra, Faculdade de Medicina
Hospital Italiano de Buenos Aires
University of the Philippines Manila
Uniwersytet Opolski
Kepler Universitätsklinikum
Erciyes University, Faculty of Medicine
Riga Stradins University
Moscow Healthcare Department
School of Medicine, Trinity College Dublin
Universitätsspital Zürich, Dermatologische Klinik
Universidad Espíritu Santo
Hamad General Hospital
Cleveland Clinic Abu Dhabi
Royal Hospital
Poltava State Medical University
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Astana Medical University
Dr. D.Y. Patil Medical College, Navi Mumbai
Clínica San Felipe
Hospital Regional Rancagua
Clinica San Carlo
Remedika General Hospital
University Dermatological Center (DermaCDU)
Center of Excellence in Asthma and Allergy Larenas Hospital Médica Sur
The University of Hong Kong
Charité – Universitätsmedizin Berlin
Erasmus MC
National and Kapodistrian University of Athens
Hiroshima University
Universidade Federal de São Paulo
Pontificia Universidad Católica de Chile
University of Cincinnati College of Medicine
Western Sydney University
Sechenov First Moscow State Medical University
Universitat Pompeu Fabra Barcelona
Johannes Kepler University Linz
Mashhad University of Medical Sciences
Guy's and St Thomas' NHS Foundation Trust
Kuwait University
Universidad de Antioquia
Centre Hospitalier Universitaire de Grenoble
Medical University of Sofia
Universidad de Los Andes, Colombia
Peking University First Hospital
Faculdade de Medicina da Universidade do Porto (FMUP)
Siriraj Hospital
Bispebjerg Hospital
King Faisal Specialist Hospital & Research Centre
Ajou University School of Medicine
Groote Schuur Hospital
Bahçeşehir Üniversitesi
Universidade de Coimbra, Faculdade de Medicina
Hospital Italiano de Buenos Aires
University of the Philippines Manila
Uniwersytet Opolski
Kepler Universitätsklinikum
Erciyes University, Faculty of Medicine
Riga Stradins University
Moscow Healthcare Department
School of Medicine, Trinity College Dublin
Universitätsspital Zürich, Dermatologische Klinik
Universidad Espíritu Santo
Hamad General Hospital
Cleveland Clinic Abu Dhabi
Royal Hospital
Poltava State Medical University
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
Astana Medical University
Dr. D.Y. Patil Medical College, Navi Mumbai
Clínica San Felipe
Hospital Regional Rancagua
Clinica San Carlo
Remedika General Hospital
University Dermatological Center (DermaCDU)
Center of Excellence in Asthma and Allergy Larenas Hospital Médica Sur
Corresponding Author(s)
Other Contributor(s)
Abstract
Background: Mobile health technologies may improve the management of chronic diseases, such as chronic spontaneous urticaria. However, effectiveness of mHealth tools largely depends on patient adherence, which can be influenced by various demographic, clinical, behavioural, psychosocial factors, and apps characteristics (appealing and simplicity of use). Understanding these adherence patterns is crucial for optimizing mHealth interventions. In this study, we aimed to assess adherence patterns associated to the use of CRUSE, a mHealth app designed for patients with CSU. Methods: We assessed users of the CRUSE app with self-reported CSU or suggested by a physician. For each user, we evaluated the number of days they completed the CRUSE daily monitoring questionnaire (app adherence) within the first 3 months after installation. We constructed univariable and multivariable ordered beta regression models to identify predictors of 3-month adherence to the app. Results: We analysed data from 2085 patients (66,114 days). Median adherence to the CRUSE app was of 22 days (24.4% of 90 days). In multivariable regression models, the variables more strongly associated with increased adherence to CRUSE included age (average increase = 0.16 percent points [pp] per additional year; 95% credible interval [CrI] = 0.08; 0.23 pp), male sex (average difference = 4.24 pp; 95% CrI = 1.77; 6.39 pp), being from a European country (average difference = 2.66 pp; 95% CrI = 0.59; 5.19 pp), and using monoclonal antibodies (average difference = 4.60 pp; 95% CrI = 2.26; 6.65 pp). Conclusions: Our findings suggest that age, male sex, residence in Europe, and the use of monoclonal antibodies are significant factors associated with increased adherence to the CRUSE app. These insights may help identify patient subgroups who would benefit most from mHealth support in managing CSU.