Seroprevalence of toxoplasma gondii using sabin feldman dye test in children and young adults in Bangphae district, Ratchaburi province, Thailand
4
Issued Date
2022
Copyright Date
2022
Resource Type
Language
eng
File Type
application/pdf
No. of Pages/File Size
ix, 72 leaves : ill.
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
Mahidol University
Bibliographic Citation
Thematic Paper (M.C.T.M. (Tropical Pediatrics))--Mahidol University, 2022)
Suggested Citation
Sugai, Misaki, 1978- Seroprevalence of toxoplasma gondii using sabin feldman dye test in children and young adults in Bangphae district, Ratchaburi province, Thailand. Thematic Paper (M.C.T.M. (Tropical Pediatrics))--Mahidol University, 2022). Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/113817
Title
Seroprevalence of toxoplasma gondii using sabin feldman dye test in children and young adults in Bangphae district, Ratchaburi province, Thailand
Author(s)
Abstract
Toxoplasmosis is an intracellular protozoan infection known for its worldwide prevalence. Even with a high disease burden, the seroprevalence of T. gondii in children has not been documented in Thailand. A retrospective cross-sectional study was conducted in Bang Phae district, Ratchaburi Province, Thailand, in 2012 and 2015. We aimed to determine the T. gondii seroprevalence in 2012 and 2015 and its demographic risks. The archived blood samples from 2012 and 2015 and demographic data from the previous study entitled "Dengue Virus Seroprevalence Study in Bang Phae district, Ratchaburi, Thailand: A Cohort Study in 2012-2015" were used. Five hundred and seventy-three subjects were randomly selected from the previous study, stratified by age group, gender, and living subdistricts. T. gondii IgG was tested using the Sabin-Feldman dye test. The seroprevalence of T. gondii was 2.8% and 4.2% in 2012 and 2015, respectively. In 2015, the highest seropositivity of 18/285 (6.3%) was found in ages 14-23 years. Of 557 initial seronegative subjects, 8 (1.4%) seroconverted. Of 16 initial seropositive subjects, 1 (6.3%) showed an increasing titer. In 2015, seroprevalence in males was higher than in females (PR 3.03, p = 0.011), especially in the subgroup aged 19-28 years (PR 4.95, p = 0.033). Living subdistrict and nutritional status did not show a significant difference in seropositivity. This study showed low T. gondii seroprevalence in children and young adults in Bang Phae district, Ratchaburi province, Thailand. A prospective clinical study should be conducted for a better understanding of risk exposure in teenage years
Degree Name
Master of Clinical Tropical Medicine
Degree Level
Master's degree
Degree Department
Faculty of Tropical Medicine
Degree Discipline
Tropical Pediatrics
Degree Grantor(s)
Mahidol University